1. 药材主信息
| 中文名称: | 山竹子 |
| 英文名称: | Manyflower Garcinia |
| 拉丁名称: | Garcinia multiflora |
| 使用部位: | bark or fruit |
| 功用: | To clear heat and engender liquid. |
| 适用症: | Stomach heat fluid damage, vomiting, thirst, lung heat qi counterflow, incessant cough. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 27542-37-6 | - | (+)-Volkensiflavone | 23844069 |
| 480-41-1 | - | (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one | 667495 |
| 220611-41-6 | GB-1a | (2R)-8-[(2S,3R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one | 124385005 |
| 18412-96-9 | GB-2a | (2S)-8-[(2S,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one | 176988 |
| 65008-17-5 | 1,6-二羟基-3,5,7-三甲氧基山酮 | 1,6-Dihydroxy-3,5,7-trimethoxyxanthen-9-one | 5316837 |
| 26271-33-0 | 2,3',4,6-Tetrahydroxybenzophenone | 2,3',4,6-Tetrahydroxybenzophenone | 440991 |
| 16851-21-1 | morelloflavone | 8-[(2S,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one | 5464454 |
| 19202-36-9 | 扁柏双黄酮 | Hinokiflavone | 5281627 |
| 519-34-6 | 桑橙素 | Maclurin | 68213 |
| 480-16-0 | 桑色素 | Morin | 5281670 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27710830 |
| CASP1 | ICE; IL1BC; P45 | 11q22.3 | 27641928 |
| HMOX1 | HMOX1D; HO-1; HSP32; bK286B10 | 22q12.3 | 27641928 |
| ICMT | HSTE14; MST098; MSTP098; PCCMT; PCMT; PPMT | 1p36.31 | 27710830 |
| IFNG | IFG; IFI | 12q15 | 21748601 |
| IL10 | CSIF; GVHDS; IL-10; IL10A; TGIF | 1q32.1 | 27641928 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 27641928 |
| IL2 | IL-2; TCGF; lymphokine | 4q27 | 21748601 |
| MAP2K7 | JNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4 | 19p13.2 | 27710830 |
| MTOR | FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS | 1p36.22 | 27710830 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Chronic liver disease | group | 21354229 |
| Colorectal Neoplasms | group | 27710830 |
| Inflammation | phenotype | 27641928 |
| Insulin Resistance | phenotype | 24985145 |
| Lung Neoplasms | group | 21748601 |
| Necrosis | phenotype | 27710830 |
| Neuroblastoma | disease | 22459762 |
| Non-alcoholic Fatty Liver Disease | disease | 31758699 |
| Obesity | disease | 24985145 |
| Polycystic Kidney, Autosomal Dominant | disease | 24116661 |
