科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 三棱
英文名称: Common Burreed Tuber
拉丁名称: Rhizoma Sparganii
使用部位: tuber
功用: To eliminate blood stasis with strong effect, promote the flow of qi, remove the retention of undigested food, and relieve pain.
适用症: Concretion conglomeration accumulation and gathering, qi-blood stagnation, pain in heart and abdomen, distending pain in rib-side, amenorrhea, postpartum blood stasis abdominal pain, knocks and falls, swelling of sores.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
1450-72-2 2'-羟基-5'-甲基苯乙酮 2'-Hydroxy-5'-methylacetophenone 15068
19670-51-0 1-棕榈酸单甘油酯 2,3-Dihydroxypropyl hexadecanoate 14900
1072-83-9 2-乙酰吡咯 2-Acetylpyrrole 14079
74805-70-2 - 5,7,2',3'-Tetrahydroxyflavone 5321864
67-47-0 5-羟甲基糠醛 5-Hydroxymethylfurfural 237332
40222-77-3 6-(羟甲基)吡啶-3-醇 6-(Hydroxymethyl)pyridin-3-ol 419490
544-71-8 异亚油酸 9,11-Octadecadienoic acid 5282796
10030-73-6 PALMITELAIDIC ACID 9-Hexadecenoic acid 5282745
520-36-5 芹菜素 Apigenin 5280443
123-99-9 壬二酸 Azelaic Acid 2266

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCB11 ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP 2q31.1 24107776
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 24107776
ABCG5 STSL; STSL2 2p21 24107776
ABCG8 GBD4; STSL; STSL1 2p21 24107776
AKR1B1 ADR; ALDR1; ALR2; AR 7q33 21712449
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 21871133
APP AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 21q21.3 24107941
BACE1 ASP2; BACE; HSPC104 11q23.3 24107941
BAX BCL2L4 19q13.33 26843455
BCL2 Bcl-2; PPP1R50 18q21.33 21871133

4. 相关疾病

疾病名称 疾病类型 参考文献
Adenocarcinoma group 21550230
Blood Pressure phenotype 28143892
Bone Resorption phenotype 31145860
Brain Ischemia disease 28186440
Carcinogenesis phenotype 28027595
Epstein-Barr Virus Infections group 28056971
Erythema phenotype 30622245
Fibrosis phenotype 28143892
Inflammation phenotype 27374313
Inflammation phenotype 28027595