1. 药材主信息
| 中文名称: | 牵牛子 |
| 英文名称: | Pharbitis seed |
| 拉丁名称: | Semen Pharbitidis |
| 使用部位: | seed |
| 功用: | To cause drastic purgation for clearing away retained fluid, and to kill worms. |
| 适用症: | Edema distention fullness, inhibited urine and stool, phlegm-rheum and accumulation-gathering, qi counterflow with cough and asthma, abdominal pain due to worm accumulation, ascariasis, taeniasis. |
| 毒副作用: | Extremely Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 2438-10-0 | (+)-萜品-4-醇 | (+)-Terpinen-4-ol | 2724161 |
| 10408-16-9 | - | (-)-Sabinene | 11051711 |
| 1730-91-2 | (S)-(+)-2-甲基丁酸 | (S)-2-methylbutanoic acid | 448893 |
| 111-27-3 | 正己醇 | 1-Hexanol | 8103 |
| 80-59-1 | 惕各酸 | 2,3-Dimethylacrylic acid, (E)- | 125468 |
| 110-43-0 | - | 2-Heptanone | 8051 |
| 473-86-9 | 3 -羟基- 2 -甲基丁酸 | 2-Methyl-3-hydroxybutyric acid | 160471 |
| 31394-54-4 | - | 2-Methylhexane | 11582 |
| 18829-56-6 | 反-2-壬烯醛 | 2-Nonenal | 5283335 |
| 3777-69-3 | 2-戊基呋喃 | 2-Pentylfuran | 19602 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
| ALPP | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 | 2q37.1 | 25832436 |
| ARG1 | - | 6q23.2 | 30377563 |
| ASRGL1 | ALP; ALP1; CRASH | 11q12.3 | 25832436 |
| ATHS | ALP | 19p13.3-p13.2 | 25832436 |
| ATRNL1 | ALP; bA338L11.1; bA454H24.1 | 10q25.3 | 25832436 |
| BAX | BCL2L4 | 19q13.33 | 30674340 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30674340 |
| BGLAP | BGP; OC; OCN | 1q22 | 25832436 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 30578827 |
| Alzheimer's Disease | disease | 30447302 |
| Brain Ischemia | disease | 21709246 |
| Carcinoma | group | 25974735 |
| Carcinoma, Papillary | disease | 25974735 |
| Charcot-Marie-Tooth Disease | disease | 31695036 |
| Chromosome Aberrations | group | 23701745 |
| Head and Neck Neoplasms | group | 24157255 |
| Inflammation | phenotype | 25128650 |
| Inflammation | phenotype | 24721152 |
