1. 药材主信息
| 中文名称: | 千金藤 |
| 英文名称: | Japanese Staphania |
| 拉丁名称: | Stephania japonica |
| 使用部位: | root or stem-leaf |
| 功用: | To clear heat and resolve toxin, dispel wind and relieve pain, disinhibit water and disperse edema. |
| 适用症: | Swelling pain in throat, swollen welling abscess, sore and boil, poisonous snake bite, wind-damp impediment pain, stomachache, beriberi with edema, nephritis with edema, urinary tract infection, rheumatic arthritis, sciatica. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 549-08-6 | - | (4aR)-3,4,4a,5,18,19-Hexahydro-9,21,22,26-tetramethoxy-4-methyl-2H-1,24:12,15-dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline | 5317122 |
| 2416-19-5 | (E)-hexadec-7-enoic acid | (Z)-7-Hexadecenoic acid | 5318393 |
| 58738-31-1 | 16-Oxoprometaphanine | 16-Oxoprometaphanine | 91895298 |
| 105454-04-4 | 7-表紫杉醇 | 7-epi-Taxol | 184492 |
| 2086-83-1 | 小檗碱 | Berberine | 2353 |
| 18556-27-9 | 汉防己丙素 | Cyclanoline | 3082134 |
| 16653-88-6 | - | Epismilagenin | 99512 |
| 1805-85-2 | - | Hasubanonine | 442246 |
| 18411-75-1 | Hautriwaic acid | Hautriwaic acid | 12310372 |
| 17132-74-0 | - | Homoaromoline | 99620 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ANXA5 | ANX5; ENX2; HEL-S-7; PP4; RPRGL3 | 4q27 | 25682924 |
| BAX | BCL2L4 | 19q13.33 | 25682924 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21496227 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 28990249 |
| CCNA1 | CT146 | 13q13.3 | 25682924 |
| CCNB1 | CCNB | 5q13.2 | 25682924 |
| CDK1 | CDC2; CDC28A; P34CDC2 | 10q21.2 | 25682924 |
| CDK4 | CMM3; PSK-J3 | 12q14.1 | 25682924 |
| CDKN1A | CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 | 6p21.2 | 25682924 |
| DNM1L | DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; OPA5 | 12p11.21 | 31037132 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinoma, Ovarian Epithelial | disease | 28990249 |
| Diabetes Mellitus, Experimental | disease | 27067643 |
| Diabetes Mellitus, Experimental | disease | 20304443 |
| Glucose tolerance test | phenotype | 20304443 |
| Hyperglycemia | disease | 27067643 |
| Insulin Resistance | phenotype | 22019891 |
| Insulin Resistance | phenotype | 20304443 |
| Left Ventricular Hypertrophy | disease | 31371114 |
| Neoplasms, Glandular and Epithelial | group | 28990249 |
| ovarian neoplasm | disease | 28990249 |
