1. 药材主信息
| 中文名称: | 欧鼠李 |
| 英文名称: | Glossy Buckthorn |
| 拉丁名称: | Rhamnus frangula [Syn. Frangula alnus] |
| 使用部位: | bark |
| 功用: | To moisten intestines and free stool. |
| 适用症: | Habitual constipation, abdominal pain. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 14400-96-5 | 4-[[(1S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl]methyl]phenol | (+)-Armepavine | 680292 |
| 518-82-1 | 大黄素 | Emodin | 3220 |
| 491-60-1 | 大黄素蒽酮 | Emodin anthrone | 122635 |
| 521-62-0 | 泻鼠李皮苷A | Frangulin A | 196979 |
| 14101-04-3 | 泻鼠李皮苷B | Frangulin B | 442744 |
| 574-84-5 | 秦皮素 | Fraxetin | 5273569 |
| 3785-24-8 | 酸模素 | Nepodin | 100780 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
| ALPP | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 | 2q37.1 | 25832436 |
| ASRGL1 | ALP; ALP1; CRASH | 11q12.3 | 25832436 |
| ATHS | ALP | 19p13.3-p13.2 | 25832436 |
| ATRNL1 | ALP; bA338L11.1; bA454H24.1 | 10q25.3 | 25832436 |
| BGLAP | BGP; OC; OCN | 1q22 | 25832436 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 30897821 |
| CCL27 | ALP; CTACK; CTAK; ESKINE; ILC; PESKY; SCYA27 | 9p13.3 | 25832436 |
| CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | 16q22.1 | 24157255 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Head and Neck Neoplasms | group | 24157255 |
| Liver neoplasms | group | 23848338 |
| Nasopharyngeal carcinoma | disease | 31731581 |
| Osteoporosis | disease | 25832436 |
