1. 药材主信息
| 中文名称: | 牛耳大黄 |
| 英文名称: | Crisped Dock |
| 拉丁名称: | Rumex crispus |
| 使用部位: | root |
| 功用: | To clear heat and resolve toxin, cool blood and stanch bleeding, free stool and kill worms. |
| 适用症: | Acute hepatitis, chronic hepatitis, enteritis, dysentery, chronic trachitis, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, heat bind constipation, swelling toxin of welling abscess and flat abscess, scab and lichen, bald sores. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 481-74-3 | 大黄酚 | Chrysophanic acid | 10208 |
| 117-10-2 | 1,8-二羟基蒽醌 | Danthron | 2950 |
| 518-82-1 | 大黄素 | Emodin | 3220 |
| 491-60-1 | 大黄素蒽酮 | Emodin anthrone | 122635 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
| ALPP | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 | 2q37.1 | 25832436 |
| ASRGL1 | ALP; ALP1; CRASH | 11q12.3 | 25832436 |
| ATHS | ALP | 19p13.3-p13.2 | 25832436 |
| ATRNL1 | ALP; bA338L11.1; bA454H24.1 | 10q25.3 | 25832436 |
| BGLAP | BGP; OC; OCN | 1q22 | 25832436 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 30897821 |
| CCL27 | ALP; CTACK; CTAK; ESKINE; ILC; PESKY; SCYA27 | 9p13.3 | 25832436 |
| CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | 16q22.1 | 24157255 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Head and Neck Neoplasms | group | 24157255 |
| Liver neoplasms | group | 23848338 |
| Nasopharyngeal carcinoma | disease | 31731581 |
| Osteoporosis | disease | 25832436 |
