科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 南沙参
英文名称: Fourleaf Ladybell Root
拉丁名称: Radix Adenophorae
使用部位: -
功用: To nourish yin and remove heat from the lung, to relieve phlegm, and to reinforce qi.
适用症: Treament of heat in the lung with dry cough, cough with scanty sticky sputum in phthisis with deficiency of yin , deficiency of both qi and yin with feverishness and thirst.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
112-31-2 癸醛 - 8175
7785-70-8 (1R)-(+)-alpha-蒎烯 (+)-alpha-Pinene 82227
6153-17-9 - (-)-beta-Phellandrene 443161
3687-48-7 - (3R)-oct-1-en-3-ol 6992244
688-82-4 - 1,1-Diethoxyheptane 69644
54815-13-3 - 1,1-Diethoxynonane 108625
81203-57-8 - 1,9-Heptadecadiene-4,6-diyn-3-ol, (3S,9Z)- 5469789
16840-84-9 - 10-Nonadecanol 85611
2363-88-4 反式-2,4-癸二烯醛 2,4-Decadienal 5283349
3891-98-3 Farnesane 2,6,10-Trimethyldodecane 19773

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 22607709
CASP3 CPP32; CPP32B; SCA-1 4q35.1 22607709
CASP9 APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 1p36.21 22607709
CCNA2 CCN1; CCNA 4q27 28492556
CCND1 BCL1; D11S287E; PRAD1; U21B31 11q13.3 26104856
CDK2 CDKN2; p33(CDK2) 12q13.2 26104856
CDK4 CMM3; PSK-J3 12q14.1 26104856
CDKN1A CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 6p21.2 26104856
CDKN2A ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16 9p21.3 29440765
DEPP1 C10orf10; DEPP; FIG; Fseg 10q11.21 29440765

4. 相关疾病

疾病名称 疾病类型 参考文献
Burkitt Lymphoma disease 22607709
Colonic Neoplasms group 29440765
leukemia disease 28492556
leukemia disease 26104856
leukemia disease 23487022
Lung Neoplasms group 29061506
Neoplasm Invasiveness phenotype 28774312
Pain phenotype 28396565