1. 药材主信息
| 中文名称: | 牡荆叶 |
| 英文名称: | Hempleaf Negundo Chastetree Leaf |
| 拉丁名称: | Folium Viticis Negundo |
| 使用部位: | - |
| 功用: | To counteract toxicity, and to induce expectoration, relieve cough and asthma. |
| 适用症: | 1. Oral administration of its eemulsion (0.52-1.73g.kg) exerts a strong expectorant effect in mice.2. Oral administration of its volatile oil (1.04g/kg) exerts a significant antitussive effect in mice with cough induced by inhalation of concentrated ammonia.3. Increasing the hypnotic effect of pentobarital sodium in mice. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 483-76-1 | (+)-DELTA-CADINENE | - | 441005 |
| 18794-84-8 | 反式-β-金合欢烯 | - | 5281517 |
| 495-61-4 | (-)-β-bisabolene | - | 10104370 |
| 2243-33-6 | - | (+)-alpha-Phellandrene | 443160 |
| 489-39-4 | (+)-Aromadendrene | (+)-Aromadendrene | 11095734 |
| 5794-03-6 | - | (+)-Camphene | 92221 |
| 2438-10-0 | (+)-萜品-4-醇 | (+)-Terpinen-4-ol | 2724161 |
| 7785-26-4 | (1S)-(-)-α-蒎烯 | (-)-alpha-Pinene | 440968 |
| 10408-16-9 | - | (-)-Sabinene | 11051711 |
| 577-27-5 | - | (1aR,4R,4aS,7R,7aS,7bS)-1,1,4,7-tetramethyl-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulen-4-ol | 92812 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB1 | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 | 7q21.12 | 22011009 |
| Abcb1b | Abcb1; Mdr1; Mdr1b; Pgy-1; Pgy1; mdr | 5 A1|5 3.43 cM | 22011009 |
| ACE2 | ACEH | Xp22.2 | 28935757 |
| ACTA2 | ACTSA | 10q23.31 | 26891034 |
| ACTG2 | ACT; ACTA3; ACTE; ACTL3; ACTSG; VSCM | 2p13.1 | 23262250 |
| ADIPOQ | ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28 | 3q27.3 | 22388319 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 29566148 |
| AHR | RP85; bHLHe76 | 7p21.1 | 24247421 |
| AHR | RP85; bHLHe76 | 7p21.1 | 31027257 |
| AKR1B1 | ADR; ALDR1; ALR2; AR | 7q33 | 21712449 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 21975863 |
| Acute Lung Injury | disease | 25512625 |
| Adenoma | group | 26223300 |
| Adenomatous Polyposis Coli | disease | 24516128 |
| Adrenoleukodystrophy | disease | 25822341 |
| Aging | phenotype | 25677910 |
| Aging | phenotype | 28677234 |
| Aging | phenotype | 28070015 |
| Aging | phenotype | 23293221 |
| Aging | phenotype | 22304913 |
