1. 药材主信息
| 中文名称: | 木鳖子 |
| 英文名称: | Momordicae Semen |
| 拉丁名称: | - |
| 使用部位: | - |
| 功用: | - |
| 适用症: | Swollen welling abscess, mammary welling abscess, scrofula, hemorrhoids and fistulas, dry lichen, bald sores. |
| 毒副作用: | Extremely Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 506-30-9 | 花生酸 | - | 10467 |
| 2416-20-8 | Hexadecenoicacid,Z-11- | (Z)-hexadec-11-enoic acid | 5312414 |
| 147527-21-7 | 10-NONADECENOIC ACID | 10-Nonadecenoic acid | 5312512 |
| 504-53-0 | 18-三十五烷酮 | 18-Pentatriacontanone | 10440 |
| 150972-72-8 | 7,8-二羟基升麻醇 | 7,8-Didehydrocimigenol | 101577840 |
| 143183-47-5 | - | 7-Oxodihydrokarounidiol | 122881 |
| 481-18-5 | α-菠菜甾醇 | alpha-Spinasterin | 5281331 |
| 112-85-6 | 二十二烷酸 | Behenic Acid | 8215 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 107-43-7 | 甜菜碱 | Betaine | 247 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| BBC3 | JFY-1; JFY1; PUMA | 19q13.32 | 24389342 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 22832932 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 27472952 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 22832932 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 27472952 |
| BIRC5 | API4; EPR-1 | 17q25.3 | 22832932 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Aging | phenotype | 24932939 |
| Alzheimer's Disease | disease | 31560162 |
| Cognition Disorders | group | 21708244 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Down Syndrome | disease | 24932939 |
| Inflammation | phenotype | 21708244 |
| leukemia | disease | 23584398 |
| leukemia | disease | 21950524 |
