1. 药材主信息
| 中文名称: | 葎草 |
| 英文名称: | Redflowered Swisscentaury |
| 拉丁名称: | Rhaponticum carthamoides |
| 使用部位: | root |
| 功用: | To boost qi and fortify spleen, quiet spirit. |
| 适用症: | Fatigue hypodynamia, inappetence, neurasthenia. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 465-18-9 | 猪苓酸C | (2R)-2-[(5R,10S,13R,14R,16R,17R)-16-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid | 9805290 |
| 18069-14-2 | (20R,22R)-2Β,3Β,5Α,14Α,20,22,25-七羟基胆甾-7-烯-6-酮 | 2beta,3beta,5beta,14,20,22R,25-Heptahydroxycholest-7-en-6-one | 441833 |
| 23044-80-6 | 筋骨草甾酮C | Ajugasterone C | 441826 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 487-52-5 | 紫铆因 | Butein | 5281222 |
| 17184-21-3 | 常春藤皂苷元-3-O-α-L-吡喃阿拉伯糖苷 | Cauloside A | 441928 |
| 465-99-6 | 常春藤皂苷元 | Hederagenin | 73299 |
| 468-28-0 | 蛇床酮 | Lupulone | 68051 |
| 4382-17-6 | 3,3'-di-O-methylquercetin | Quercetin 3,3'-dimethyl ether | 5316900 |
| 67968-40-5 | 西贝母碱苷 | Sipeimine-3β-D-glucoside | 132538 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24919544 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27465039 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 30158592 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21871133 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 21871133 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 22114764 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 22114764 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 22114764 |
| CAT | - | 11p13 | 29179721 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Blood Pressure | phenotype | 28143892 |
| Epstein-Barr Virus Infections | group | 28056971 |
| Fibrosis | phenotype | 28143892 |
| Inflammation | phenotype | 27374313 |
| Insulin Resistance | phenotype | 30158592 |
| Liver neoplasms | group | 21131551 |
| Lung Neoplasms | group | 21550230 |
| Multiple Myeloma | disease | 21871133 |
| Neoplasm Metastasis | phenotype | 31182131 |
