1. 药材主信息
| 中文名称: | 蓼大青叶 |
| 英文名称: | Indigoplant Leaf |
| 拉丁名称: | Folium Polygoni Tinctorii |
| 使用部位: | - |
| 功用: | To remove toxic heat, and to cause subsidence of eruptions by reducing heat in blood. |
| 适用症: | Treatment of fever and eruptions in epidemic diseases, cough and asthma due to heat in the lung, inflammation of the throat, mnmps, erysipelas, carbuncle. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 20307-14-6 | - | (2R,3R,5S,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-(1H-indol-3-yloxy)oxan-4-one | 101529308 |
| 480-93-3 | 3-羟基吲哚 | 1H-Indol-3-ol | 50591 |
| 99282-79-8 | 2-(CARBOXYMETHYL-AMINO)-4-CHLORO-BENZOIC ACID | 2-((Carboxymethyl)amino)-4-chlorobenzoic acid | 11107141 |
| 13710-70-8 | 印度榅桲素 | 2-(2-Hydroxypropan-2-yl)-2,3-dihydrofuro[3,2-g]chromen-7-one | 604512 |
| 41547-82-4 | 腺苷 | Adenosine | 60961 |
| 480-10-4 | 紫云英苷 | Astragalin | 5282102 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 635-65-4 | 胆红素 | Bilirubin | 5280352 |
| 474-25-9 | 鹅去氧胆酸 | Chenodiol | 10133 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 21649640 |
| AHR | RP85; bHLHe76 | 7p21.1 | 22533375 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24569474 |
| AREG | AR; AREGB; CRDGF; SDGF | 4q13.3 | 24520077 |
| BAX | BCL2L4 | 19q13.33 | 21614569 |
| BAX | BCL2L4 | 19q13.33 | 31963815 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 31570787 |
| CCK | - | 3p22.1 | 23783097 |
| CFTR | ABC35; ABCC7; CF; CFTR/MRP; MRP7; TNR-CFTR; dJ760C5.1 | 7q31.2 | 31268738 |
| CHRNA7 | CHRNA7-2; NACHRA7 | 15q13.3 | 31560162 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Aging | phenotype | 24932939 |
| Alzheimer's Disease | disease | 31560162 |
| Body Weight | phenotype | 21614569 |
| Colitis, Collagenous | disease | 21366635 |
| Constipation | phenotype | 23041323 |
| Diarrhea | phenotype | 31268738 |
| Diarrhea | phenotype | 28378364 |
| Down Syndrome | disease | 24932939 |
| Fatty Liver Disease | disease | 22531947 |
| Gastrointestinal Neoplasms | group | 24520077 |
