1. 药材主信息
| 中文名称: | 苦参实 |
| 英文名称: | Lightyellow Sophora Seed |
| 拉丁名称: | Sophora flavescens [Syn. Sophora angustfolia] |
| 使用部位: | seed |
| 功用: | To clear heat and resolve toxin, free stool, kill worms. |
| 适用症: | Acute bacillary dysentery, constipation, ascariasis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 2363-88-4 | 反式-2,4-癸二烯醛 | 2,4-Decadienal | 5283349 |
| 106-24-1 | 香叶醇 | Geraniol | 637566 |
| 25243-95-2 | - | L-Octanoylcarnitine | 11953814 |
| 143-07-7 | 月桂酸 | Lauric Acid | 3893 |
| 108-38-3 | - | m-Xylene | 7929 |
| 519-02-8 | 苦参碱 | Matrine | 91466 |
| 112-05-0 | 壬酸 | Nonanoic acid | 8158 |
| 106-42-3 | - | P-Xylene | 7809 |
| 145572-44-7 | 槐果碱 | Sophocarpine | 115269 |
| 6882-68-4 | 槐定碱 | Sophoridine | 165549 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26945965 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 26945965 |
| EPHB2 | BDPLT22; CAPB; DRT; EK5; EPHT3; ERK; Hek5; PCBC; Tyro5 | 1p36.12 | 28893319 |
| GCG | GLP-1; GLP1; GLP2; GRPP | 2q24.2 | 23471488 |
| GSK3B | - | 3q13.33 | 26945965 |
| ITK | EMT; LPFS1; LYK; PSCTK2 | 5q33.3 | 26945965 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 28893319 |
| MAPK14 | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA | 6p21.31 | 28571917 |
| MAPK8 | JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c | 10q11.22 | 28893319 |
| MIR21 | MIRN21; hsa-mir-21; miR-21; miRNA21 | 17q23.1 | 28571917 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Head and Neck Neoplasms | group | 28571917 |
| Hyperglycemia | disease | 23471488 |
| Liver neoplasms | group | 26945965 |
| Pancreatic Neoplasm | disease | 28893319 |
