1. 药材主信息
| 中文名称: | 苦豆子 |
| 英文名称: | Foxtail-like Sophora |
| 拉丁名称: | Sophora alopecuroides |
| 使用部位: | whole herb and seed |
| 功用: | To clear heat and dry damp, kill worms and relieve pain. |
| 适用症: | Dysentery, stomachache, excessive leukorrhea, eczema, sore and boil, intractable lichen. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 63296-15-1 | 5,6-Dihydroxy-3,7,3',4'-tetramethoxyflavone | 5,6-Dihydroxy-3,3',4',7-tetramethoxyflavone | 14376225 |
| 3153-73-9 | 松风草内酯 | 7-Methoxy-8-(7-methoxy-2-oxochromen-6-yl)chromen-2-one | 5319307 |
| 487-52-5 | 紫铆因 | Butein | 5281222 |
| 58480-54-9 | 12,13-去氢苦参碱 | Matridin-15-one, 12,13-didehydro- | 3041752 |
| 519-02-8 | 苦参碱 | Matrine | 91466 |
| 59-67-6 | 维生素B3 | Nicotinic acid | 938 |
| 483-89-6 | - | Oxynarcotine | 5320347 |
| 50-56-6 | Oxytocin | Oxytocin | 439302 |
| 474-58-8 | 刺五加苷A(胡萝卜苷） | Sitogluside | 5742590 |
| 145572-44-7 | 槐果碱 | Sophocarpine | 115269 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25886453 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24919544 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27465039 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 30158592 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26945965 |
| BAX | BCL2L4 | 19q13.33 | 21714853 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21714853 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30822359 |
| BIRC7 | KIAP; LIVIN; ML-IAP; MLIAP; RNF50 | 20q13.33 | 21714853 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 22114764 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Head and Neck Neoplasms | group | 28571917 |
| Insulin Resistance | phenotype | 30158592 |
| Liver neoplasms | group | 26945965 |
| Liver neoplasms | group | 21131551 |
| Multiple Myeloma | disease | 25886453 |
| Neoplasm Metastasis | phenotype | 21131551 |
| Obesity | disease | 30158592 |
| Obesity | disease | 27159578 |
| Pancreatic Neoplasm | disease | 21714853 |
| Pancreatic Neoplasm | disease | 28893319 |
