1. 药材主信息
| 中文名称: | 苦地丁 |
| 英文名称: | all - grass of Bunge Corydalis |
| 拉丁名称: | Herba Corydalis bungeae |
| 使用部位: | whole herb |
| 功用: | - |
| 适用症: | Influenza, infection of upper respiratory tract, tonsillitis, infective hepatitis, enteritis, dysentery, nephritis, parotitis, conjunctivitis, acute appendicitis, clove sore and swollen welling abscess, scrofula. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 37687-34-6 | 6-Acetonyldihydrosanguinarine | (+/-)-6-Acetonyldihydrosanguinarine | 181538 |
| 483-44-3 | - | (S)-Cheilanthifoline | 440582 |
| 6451-73-6 | 金黄紫堇碱 | (S)-Scoulerine | 439654 |
| 5289-74-7 | 蜕皮激素（β-蜕皮甾酮） | 20-Hydroxyecdysone | 5459840 |
| 3934-84-7 | 3-O-甲基没食子酸 | 3,4-Dihydroxy-5-methoxybenzoic acid | 19829 |
| 536-66-3 | 4-异丙基苯甲酸 | 4-Isopropylbenzoic acid | 10820 |
| 18797-80-3 | 乙酰紫堇灵 | Acetylcorynoline | 177015 |
| 485-49-4 | 荷包牡丹碱 | Bicuculline | 10237 |
| 51151-82-7 | - | Chelidonine, 13-methyl-, (14beta)- | 56842002 |
| 51151-82-7 | - | Chelidonine, 13-methyl-, (14beta)- | 56842002 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AHR | RP85; bHLHe76 | 7p21.1 | 30831189 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26945965 |
| BAX | BCL2L4 | 19q13.33 | 21714853 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21714853 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30822359 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 22033245 |
| BIRC7 | KIAP; LIVIN; ML-IAP; MLIAP; RNF50 | 20q13.33 | 21714853 |
| CALCA | CALC1; CGRP; CGRP-I; CGRP-alpha; CGRP1; CT; KC; PCT | 11p15.2 | 31504241 |
| CASP1 | ICE; IL1BC; P45 | 11q22.3 | 31336157 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 23701745 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 30578827 |
| Brain Ischemia | disease | 30239332 |
| Cardiac fibrosis | disease | 31504241 |
| Chromosome Aberrations | group | 23701745 |
| Diabetes Mellitus, Experimental | disease | 22882757 |
| Gastroparesis | disease | 30831189 |
| Head and Neck Neoplasms | group | 28571917 |
| Infarction, Middle Cerebral Artery | disease | 26234631 |
| Ischemic stroke | disease | 30239332 |
| Liver neoplasms | group | 26945965 |
