1. 药材主信息
| 中文名称: | 开口箭 |
| 英文名称: | Chinese Tupistra |
| 拉丁名称: | Tupistra chinensis |
| 使用部位: | rhizome |
| 功用: | To clear heat and resolve toxin, dispel wind and eliminate damp, dissipate stasis and relieve pain. |
| 适用症: | Diphtheria, swelling pain in throat, wind-damp impediment pain, knocks and falls, stomachache, swollen welling abscess and sore toxin, poisonous snake bites, rabid dog bite. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 645-08-9 | 异香草酸 | 3-Hydroxy-4-methoxybenzoic acid | 12575 |
| 2420-42-0 | 9(E),12(Z)-Octadecadienoic acid | 9Z,12E-octadecadienoic acid | 5282797 |
| 1125-74-2 | - | Allylpyrocatechol | 292101 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 154-23-4 | (+)-儿茶素 | Cianidanol | 9064 |
| 17149-95-0 | - | Convallagenin A | 441880 |
| 17934-59-7 | (25S)-5β-Spirostane-1β,3β,4β,5-tetrol | Convallagenin B | 12303876 |
| 143-62-4 | 毛地黄毒苷配基 | Digitoxigenin | 4369270 |
| 112-79-8 | 反油酸 | Elaidic Acid | 637517 |
| 506-46-7 | 蜡酸 | Hexacosanoic acid | 10469 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31438982 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| CEBPA | C/EBP-alpha; CEBP | 19q13.11 | 29141998 |
| CTTN | EMS1 | 11q13.3 | 30285892 |
| FGF2 | BFGF; FGF-2; FGFB; HBGF-2 | 4q28.1 | 31438982 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Cerebral Hemorrhage | phenotype | 28610608 |
| Corneal Neovascularization | disease | 31438982 |
| Glioma | disease | 31438982 |
| Liver diseases | group | 24107776 |
| Lung Neoplasms | group | 30285892 |
| melanoma | disease | 30081934 |
| Obesity | disease | 29141998 |
