1. 药材主信息
| 中文名称: | 虎杖 |
| 英文名称: | rhizome of Gaint Knotweed |
| 拉丁名称: | Rhizoma Polygoni cuspidati |
| 使用部位: | rhizome |
| 功用: | To dispel wind and damp, to eliminate blood stasis and alleviate pain, to relieve cough, and to resolve phlegm. |
| 适用症: | Hyperlipemia, impediment pain in joints, damp-heat jaundice, toxic jaundice, child jaundice, amenorrhea, hepatitis, appendicitis, candida vaginitis, concretion and conglomeration, cough with profuse phlegm, burns and scalds, knocks and falls, swelling toxin of welling abscess and sore. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 751-29-1 | - | (2E)-3-[(3aS,5aR,6R,7R,9aR,9bR,10aS)-3-(Furan-3-yl)-7-(2-hydroxypropan-2-yl)-3a,6,9a-trimethyl-1,9-dioxododecahydronaphtho[2,1-c]oxireno[d]pyran-6-yl]prop-2-enoic acid | 54611038 |
| 97-67-6 | L-苹果酸 | (2S)-2-Hydroxybutanedioic acid | 222656 |
| 82373-94-2 | 2,3,5,4-四羟基二苯乙烯葡萄糖苷 | 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside | 5321884 |
| 303-07-1 | 2,6-二羟基苯甲酸 | 2,6-Dihydroxybenzoic acid | 9338 |
| 303-07-1 | 2,6-二羟基苯甲酸 | 2,6-Dihydroxybenzoic acid | 9338 |
| 824-46-4 | 2-甲氧基对苯二酚 | 2-Methoxyhydroquinone | 69988 |
| 99-50-3 | 原儿茶酸 | 3,4-Dihydroxybenzoic acid | 72 |
| 21553-46-8 | 3,5-二甲基-4-甲氧基苯甲酸 | 3,5-Dimethyl-4-methoxybenzoic acid | 88944 |
| 21553-46-8 | 3,5-二甲基-4-甲氧基苯甲酸 | 3,5-Dimethyl-4-methoxybenzoic acid | 88944 |
| 100-06-1 | 4-甲氧基苯乙酮 | 4'-Methoxyacetophenone | 7476 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB1 | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 | 7q21.12 | 22011009 |
| Abcb1b | Abcb1; Mdr1; Mdr1b; Pgy-1; Pgy1; mdr | 5 A1|5 3.43 cM | 22011009 |
| ACE2 | ACEH | Xp22.2 | 28935757 |
| ACTA2 | ACTSA | 10q23.31 | 26891034 |
| ACTG2 | ACT; ACTA3; ACTE; ACTL3; ACTSG; VSCM | 2p13.1 | 23262250 |
| ADIPOQ | ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28 | 3q27.3 | 22388319 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 29566148 |
| AHR | RP85; bHLHe76 | 7p21.1 | 24247421 |
| AHR | RP85; bHLHe76 | 7p21.1 | 31027257 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Abdominal Pain | phenotype | 28164346 |
| Acute kidney injury | disease | 21975863 |
| Acute Lung Injury | disease | 25512625 |
| Adenocarcinoma | group | 21550230 |
| Adenoma | group | 26223300 |
| Adenomatous Polyposis Coli | disease | 24516128 |
| Adrenoleukodystrophy | disease | 25822341 |
| Aging | phenotype | 25677910 |
| Aging | phenotype | 28677234 |
| Aging | phenotype | 28070015 |
