1. 药材主信息
| 中文名称: | 琥珀 |
| 英文名称: | Amber, Succinus |
| 拉丁名称: | Succinus |
| 使用部位: | Pinus spp. |
| 功用: | 1. Treatment of infantile convulsions and epilepsy. Amber (Hupo) is used with Centipede (Wugong) and Scorpion (Quanxie). 2. Treatment of palpitations, insomnia and dream-disturbed sleep. Amber (Hupo) is used with Wild jujube seed (Suanzaoren) and Multiflower knotweed (Yejiaoteng). 3. Treatment of dysmenorrhea or amenorrhea due to blood stagnation. Amber (Hupo) is used with Chinese angelica root (Danggui), Zedoary (Ezhu) and Lindera root (Wuyao) in the formula Hupo San. 4. Treatment of urinary tract disorders manifested as frequent urination, painful urination, bloody urine or calculus formation in the urinary tract. Amber (Hupo) is used with Lysimachia (Jinqiancao), Clematis stem (Mutong) and Imperata rhizome (Baimaogen). |
| 适用症: | Sedative and diuretic. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 1135-66-6 | Isolongifolene | (-)-Isolongifolene | 11127402 |
| 620-14-4 | 3-乙基甲苯 | 3-Ethyltoluene | 12100 |
| 5362-50-5 | - | 4-Methyl-3-pentenal | 21457 |
| 562-74-3 | 4-松油醇 | 4-Terpineol, (+/-)- | 11230 |
| 110-93-0 | - | 6-Methyl-5-hepten-2-one | 9862 |
| 928-68-7 | 6-甲基-2-庚酮 | 6-Methylheptan-2-one | 13572 |
| 10208-80-7 | - | alpha-Muurolene | 12306047 |
| 473-13-2 | - | alpha-Selinene | 10856614 |
| 523-47-7 | - | beta-Cadinene | 10657 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| CNR2 | CB-2; CB2; CX5 | 1p36.11 | 31883107 |
| CTBP1 | BARS; HADDTS | 4p16.3 | 29988033 |
| IFNG | IFG; IFI | 12q15 | 28240768 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 28240768 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 31883118 |
| IL6 | BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 | 7p15.3 | 28240768 |
| MMP3 | CHDS6; MMP-3; SL-1; STMY; STMY1; STR1 | 11q22.2 | 29988033 |
| NLRP3 | AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; FCU; KEFH; MWS; NALP3; PYPAF1 | 1q44 | 31883118 |
| TNF | DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F | 6p21.33 | 28240768 |
| TRPM8 | LTRPC6; LTrpC-6; TRPP8; trp-p8 | 2q37.1 | 28240768 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Edema | phenotype | 28240768 |
| Inflammation | phenotype | 28240768 |
| Lung Neoplasms | group | 29988033 |
| Smoking | phenotype | 21903934 |
