1. 药材主信息
| 中文名称: | 鬼臼 |
| 英文名称: | Common Dysosma |
| 拉丁名称: | Dysosma versipellis [Syn. Podophyllum versipelle ] |
| 使用部位: | rhizome and root |
| 功用: | See Dysosma pleiantha. |
| 适用症: | See Dysosma pleiantha . |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 477-49-6 | 鬼臼脂毒酮 | - | 443014 |
| 21637-25-2 | - | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one | 51402807 |
| 117669-31-5 | 4’-去甲基去氢鬼臼毒素 | 4'-Demethyldehydropodophyllotoxin | 15232507 |
| 3590-93-0 | - | 4'-Demethyldeoxypodophyllotoxin | 160705 |
| 480-10-4 | 紫云英苷 | Astragalin | 5282102 |
| 477-90-7 | 岩白菜素 | Bergenin | 66065 |
| 518-29-6 | - | beta-Peltatin | 92122 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 30021-77-3 | - | Cleistanthin B | 119458 |
| 19186-35-7 | 去氧鬼臼毒素，去氧鬼臼脂素 | Deoxypodophyllotoxin | 345501 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 21445586 |
| CASR | CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1; hCasR | 3q13.33-q21.1 | 21445586 |
| CXCL1 | FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 | 4q13.3 | 25281414 |
| IFNG | IFG; IFI | 12q15 | 25281414 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 25281414 |
| MPO | - | 17q22 | 25281414 |
| PGD | 6PGD | 1p36.22 | 27270429 |
| PPARGC1A | LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1 | 4p15.2 | 28049156 |
| S100A8 | 60B8AG; CAGA; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; P8 | 1q21.3 | 25281414 |
| SIRT1 | SIR2; SIR2L1; SIR2alpha | 10q21.3 | 28049156 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 30447302 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| leukemia | disease | 27270429 |
| Liver Neoplasms, Experimental | phenotype | 21445586 |
| Obesity | disease | 28049156 |
| Ventricular Remodeling | phenotype | 26185015 |
