1. 药材主信息
| 中文名称: | 构树果 |
| 英文名称: | Common Papermulberry Fruit |
| 拉丁名称: | Broussonetia papyrifera |
| 使用部位: | fruit |
| 功用: | To enrich yin and supplement kidney, clear liver and brighten eyes, fortify spleen and disinhibit water. |
| 适用症: | Limp aching lumbus and knees due to kidney vacuity, impotence, dim vision, eye screen, edema, scant urine. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 73731-87-0 | Broussonin A | 2-[3-(4-Hydroxyphenyl)propyl]-5-methoxyphenol | 5315502 |
| 2196-14-7 | 7,4'-二羟基黄酮 | 4',7-Dihydroxyflavone | 5282073 |
| 76045-50-6 | 构树素 | Broussin | 442277 |
| 73731-86-9 | Broussonin B | Broussonin B | 5315503 |
| 76045-49-3 | Broussonin C | Broussonin C | 442289 |
| 480-39-7 | 乔松素 | Pinocembrin | 68071 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AGER | RAGE; SCARJ1 | 6p21.32 | 22989295 |
| AGER | RAGE; SCARJ1 | 6p21.32 | 31035509 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 29807112 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 22989295 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 22989295 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 31035509 |
| CASP7 | CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3 | 10q25.3 | 31035509 |
| ERN1 | IRE1; IRE1P; IRE1a; hIRE1p | 17q23.3 | 29807112 |
| HSPB1 | CMT2F; HEL-S-102; HMN2B; HS.76067; HSP27; HSP28; Hsp25; SRP27 | 7q11.23 | 22989295 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 28007523 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Encephalitis | disease | 28455264 |
| Intracranial Hemorrhage | group | 28007523 |
| melanoma | disease | 29807112 |
| Melanoma, Experimental | disease | 29807112 |
| Nerve Degeneration | phenotype | 22989295 |
| Skin Neoplasms | group | 29807112 |
