1. 药材主信息
| 中文名称: | 葛根 |
| 英文名称: | root of lobed kudzuvine |
| 拉丁名称: | Radix Puerariae |
| 使用部位: | tuberoid |
| 功用: | To relieve fever, to promote the production of body fluid,to facilitate eruption, and to arrest diarrhea. |
| 适用症: | Angina pectoris, hypertension, headache due to externally contracted wind-heat, rigidity of neck, thirst, diabetes mellitus, non-eruption of measles, heat dysentery, diarrhea, deafness in early stage, optic nerve atrophy, retinitis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 506-30-9 | 花生酸 | - | 10467 |
| 41347-45-9 | 块葛黄酮 | (6aS)-6a,13aalpha-Dihydro-10,10-dimethyl-6H,10H-furo[3,2-c | 14630495 |
| 2543-95-5 | (S)-4-甲氧基黄檀醌 | (S)-4-Methoxydalbergione | 10400054 |
| 21913-98-4 | 3'-Methoxydaidzein | 3'-Methoxydaidzein | 5319422 |
| 117047-07-1 | 3'-甲氧基葛根素 | 3'-Methoxypuerarin | 5319485 |
| 7295-76-3 | - | 3-Methoxypyridine | 23719 |
| 92117-94-7 | 4'-O-甲基葛根素 | 4'-Methoxypuerarin | 5319486 |
| 616-03-5 | 5-甲基乙内酰脲 | 5-Methylhydantoin | 69216 |
| 75187-63-2 | 7,8-二羟基-3-(4-羟基苯基)苯并吡喃-4-酮 | 7,8,4'-Trihydroxyisoflavone | 5466139 |
| 53681-67-7 | daidzein-4,7-diglucoside | 7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one | 171292 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCA1 | ABC-1; ABC1; CERP; HDLCQTL13; HDLDT1; HPALP1; TGD | 9q31.1 | 26558782 |
| ABCG1 | ABC8; WHITE1 | 21q22.3 | 26558782 |
| APOE | AD2; APO-E; ApoE4; LDLCQ5; LPG | 19q13.32 | 26558782 |
| ARG1 | - | 6q23.2 | 31629735 |
| CEBPB | C/EBP-beta; IL6DBP; NF-IL6; TCF5 | 20q13.13 | 31629735 |
| IL10 | CSIF; GVHDS; IL-10; IL10A; TGIF | 1q32.1 | 31629735 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 31629735 |
| IL6 | BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 | 7p15.3 | 31629735 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 22931352 |
| NCF1 | NCF1A; NOXO2; SH3PXD1A; p47phox | 7q11.23 | 22609359 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Body Weight | phenotype | 21557739 |
| Fatty Liver | disease | 21557739 |
| Hypoxia | phenotype | 22743170 |
| Myocardial fibrosis | phenotype | 31629735 |
| Obesity | disease | 21557739 |
| Reperfusion Injury | disease | 22743170 |
| Ventricular Remodeling | phenotype | 31629735 |
