1. 药材主信息
| 中文名称: | 钝叶决明 |
| 英文名称: | Obtuseleaf Senna Equivalent plant: Cassia tora |
| 拉丁名称: | Cassia obtusifolia |
| 使用部位: | ripe seed |
| 功用: | To clear liver and brighten eyes, disinhibit water and free stool. |
| 适用症: | Red eyes with gall, delacrimation and photophobia, clear-eye blindness, night blindness, dizziness and headache, dim vision, cirrhosis with ascites, inhibited urination, habitual constipation, toxin swelling, skin lichen. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 80503-54-4 | - | 1H-Naphtho(2,3-c)pyran-1-one, 3,4-dihydro-9,10-dihydroxy-7-methoxy-3-methylene- | 157661 |
| 481-72-1 | 芦荟大黄素 | Aloe emodin | 10207 |
| 129025-96-3 | 橙黄决明素-6-葡萄糖苷 | Aurantio-obtusin beta-D-glucoside | 442725 |
| 96820-54-1 | - | Chryso-obtusin glucoside | 442730 |
| 4839-60-5 | 大黄酚-1-O-葡萄糖苷 | Chrysophanein | 6324923 |
| 481-74-3 | 大黄酚 | Chrysophanic acid | 10208 |
| 518-82-1 | 大黄素 | Emodin | 3220 |
| 521-61-9 | 大黄素甲醚 | Physcione | 10639 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
| ALPP | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 | 2q37.1 | 25832436 |
| ASRGL1 | ALP; ALP1; CRASH | 11q12.3 | 25832436 |
| ATHS | ALP | 19p13.3-p13.2 | 25832436 |
| ATRNL1 | ALP; bA338L11.1; bA454H24.1 | 10q25.3 | 25832436 |
| BGLAP | BGP; OC; OCN | 1q22 | 25832436 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 30897821 |
| CCL27 | ALP; CTACK; CTAK; ESKINE; ILC; PESKY; SCYA27 | 9p13.3 | 25832436 |
| CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | 16q22.1 | 24157255 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Head and Neck Neoplasms | group | 24157255 |
| leukemia | disease | 27270429 |
| Liver neoplasms | group | 23848338 |
| Nasopharyngeal carcinoma | disease | 31731581 |
| Osteoporosis | disease | 25832436 |
