科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 大叶桉叶
英文名称: Swamp Mahogany Leaf
拉丁名称: Eucalyptus robusta
使用部位: leaf
功用: To soothe wind and resolve exterior, relieve cough and dispel phlegm, clear heat and resolve toxin, kill worms and relieve itch.
适用症: Common cold, ardent fever with headache, lung heat cough asthma, abdominal pain and diarrhea, malaria, wind-damp impediment pain, filariasis, leptospirosis, swelling pain in throat, red eyes, eye screen, welling abscess of ear, erysipelas, swollen welling abscess, mammary welling abscess, measles papules, wind papules, eczema, scab and lichen, scalds.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
470-82-6 桉油精;桉叶素 Eucalyptol 2758
149-91-7 没食子酸 Gallic Acid 370
49620-13-5 - Robustaflavone 5281694
78411-76-4 - Robustaol A 442541
2255-50-7 8-羟基白鲜碱 Robustine 164950

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
IFNG IFG; IFI 12q15 28240768
IL1B IL-1; IL1-BETA; IL1F2; IL1beta 2q14.1 28240768
IL1B IL-1; IL1-BETA; IL1F2; IL1beta 2q14.1 31883118
IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 7p15.3 28240768
NLRP3 AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; FCU; KEFH; MWS; NALP3; PYPAF1 1q44 31883118
TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F 6p21.33 28240768
TRPM8 LTRPC6; LTrpC-6; TRPP8; trp-p8 2q37.1 28240768
TRPV1 VR1 17p13.2 31883118

4. 相关疾病

疾病名称 疾病类型 参考文献
Alzheimer's Disease disease 30447302
Edema phenotype 28240768
Inflammation phenotype 28240768
Smoking phenotype 21903934