1. 药材主信息
| 中文名称: | 大草寇 |
| 英文名称: | Beautiful Galangal |
| 拉丁名称: | Alpinia speciosa |
| 使用部位: | seed |
| 功用: | To dissipate cold and dry damp, dispel phlegm and interrupt malaria, fortify spleen and warm stomach. |
| 适用症: | Cold pain in heart and abdomen, distention fullness in chest and abdomen, cold-damp accumulation and obstruction, indigestion, vomiting and diarrhea. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 1090-65-9 | 山姜素 | 7-Hydroxy-5-methoxy-2-phenylchroman-4-one | 4053302 |
| 18956-16-6 | 小豆蔻明 | Cardamonin | 641785 |
| 507-70-0 | - | CID 44630107 | 44630107 |
| 15345-89-8 | 去甲氧基醉椒素 | Demethoxyyangonin | 5273621 |
| 6753-98-6 | α-石竹烯 | Humulene | 5281520 |
| 103-26-4 | 肉桂酸甲酯 | Methyl cinnamate | 637520 |
| 607-91-0 | 肉豆蔻醚 | Myristicin | 4276 |
| 544-64-9 | 肉豆蔻油酸 | Myristoleic acid | 5281119 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AHR | RP85; bHLHe76 | 7p21.1 | 30166541 |
| CREB1 | CREB; CREB-1 | 2q33.3 | 30166541 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 25257174 |
| DDIT3 | AltDDIT3; C/EBPzeta; CEBPZ; CHOP; CHOP-10; CHOP10; GADD153 | 12q13.3 | 21797841 |
| DNMT1 | ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI | 19p13.2 | 30166541 |
| HIF1A | HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 | 14q23.2 | 31455352 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 31384534 |
| MTOR | FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS | 1p36.22 | 31455352 |
| NFE2L2 | HEBP1; IMDDHH; NRF2; Nrf-2 | 2q31.2 | 31455352 |
| NFKB1 | CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB | 4q24 | 25257174 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Colitis | disease | 30166541 |
| Colonic Neoplasms | group | 21797841 |
| Pain | phenotype | 28396565 |
| Septic Shock | phenotype | 31384534 |
| Triple Negative Breast Neoplasms | disease | 31455352 |
