1. 药材主信息
| 中文名称: | 刺蒺藜 |
| 英文名称: | Puncturevine Caltrap |
| 拉丁名称: | Tribulus terrestris |
| 使用部位: | fruit |
| 功用: | To dissipate wind and brighten eyes, precipitate qi and move blood. |
| 适用症: | Headache, itchy body, red eyes and eye screen, convulsion, fullness in chest, cough and counterflow, concretion and conglomeration, difficult lactation, welling abscess and flat abscess, scrofula. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 39937-47-8 | - | (2S,3R,4S,5R,6R)-2-[(2S,3R,4S,5R,6R)-2-[(2R,3R,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(1R,2S,4S,5'R,6R,7S,8R,9S,12S,13S,15R,16R,18S)-15-hydroxy-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16-yl]oxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol | 441888 |
| 1081-34-1 | α-三联噻吩 | 2,2':5',2''-Terthiophene | 65067 |
| 42369-86-8 | Diferuloylputrescine | Bis-ferulamidobutane | 5321825 |
| 19057-60-4 | 薯蓣皂苷 | Dioscin | 119245 |
| 28591-01-7 | - | F-Gitonin | 44559009 |
| 19083-00-2 | 纤细薯蓣皂苷 | Gracillin | 159861 |
| 87-52-5 | 芦竹碱 | Gramine | 6890 |
| 486-84-0 | 哈尔满碱 | Harman | 5281404 |
| 442-51-3 | 去氢骆驼蓬碱 | Harmine | 5280953 |
| 487-03-6 | 哈尔酚 | Harmol | 68094 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABL1 | ABL; BCR-ABL; CHDSKM; JTK7; bcr/abl; c-ABL; c-ABL1; p150; v-abl | 9q34.12 | 28796245 |
| ACADM | ACAD1; MCAD; MCADH | 1p31.1 | 24146112 |
| AHSA1 | AHA1; C14orf3; hAha1; p38 | 14q24.3 | 29158824 |
| AIMP2 | HLD17; JTV-1; JTV1; P38 | 7p22.1 | 29158824 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 23552851 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27155058 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 28095588 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 29497056 |
| APAF1 | APAF-1; CED4 | 12q23.1 | 28095588 |
| APAF1 | APAF-1; CED4 | 12q23.1 | 30503840 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 26348276 |
| Bone neoplasms | group | 29497056 |
| Cardiotoxicity | disease | 29524841 |
| Diabetes | disease | 25751815 |
| Fatty Liver, Alcoholic | disease | 24146112 |
| Infarction, Middle Cerebral Artery | disease | 25772012 |
| Ischemic stroke | disease | 25772012 |
| Kidney Diseases | group | 27431331 |
| Liver neoplasms | group | 30710454 |
| Lung Neoplasms | group | 23552851 |
