1. 药材主信息
| 中文名称: | 椿皮 |
| 英文名称: | Ailanthus bark, Tree of heaven bark |
| 拉丁名称: | Cortex Tooe Sinensis |
| 使用部位: | - |
| 功用: | To remove damp-heat and arrest discharges. |
| 适用症: | Treatment of morbid leukorrhea, diarrhea caused by damp-heat, chronic diarrhea, chronic dysentery, hematochezia, abnormal uterine bleeding. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 483-76-1 | (+)-DELTA-CADINENE | - | 441005 |
| 18794-84-8 | 反式-β-金合欢烯 | - | 5281517 |
| 489-39-4 | (+)-Aromadendrene | (+)-Aromadendrene | 11095734 |
| 1460-97-5 | - | (-)-gamma-Cadinene | 92313 |
| 130930-56-2 | - | 1,7,7-Trimethyl-2-vinylbicyclo[2.2.1]hept-2-ene | 576719 |
| 50892-83-6 | 1-乙酰基-beta-咔啉 | 1-(9H-pyrido[3,4-b]indol-1-yl)ethanone | 638667 |
| 80787-59-3 | 1-Hydroxycanthin-6-one | 1-Hydroxycanthin-6-one | 86014459 |
| 60755-86-4 | - | 1-Methoxycanthinone | 483522 |
| 28351-05-5 | 三十烷醇 | 1-Triacontanol | 68972 |
| 18385-89-2 | - | 2H-1-Benzopyran, 7-methoxy- | 5314753 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Body Weight | phenotype | 24559844 |
| Cognition Disorders | group | 21708244 |
| Colitis | disease | 25281414 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Inflammation | phenotype | 21708244 |
