1. 药材主信息
| 中文名称: | 川芎 |
| 英文名称: | Chuanxiong rhizome, Szechuan lovage root |
| 拉丁名称: | Radix chuanxiong；Rhizoma Chuanxiong |
| 使用部位: | rhizome |
| 功用: | 1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain |
| 适用症: | Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 13877-91-3 | 罗勒烯 | - | 5281553 |
| 18794-84-8 | 反式-β-金合欢烯 | - | 5281517 |
| 502-61-4 | α－法呢烯 | - | 5281516 |
| 106-22-9 | β-香茅醇 | - | 8842 |
| 99-83-2 | 水芹烯 | - | 7460 |
| 498-15-7 | (1S)-(+)-3-蒈烯 | (+)-3-Carene | 443156 |
| 498-15-7 | (1S)-(+)-3-蒈烯 | (+)-3-Carene | 443156 |
| 50894-66-1 | - | (+)-alpha-Funebrene | 6552024 |
| 2243-33-6 | - | (+)-alpha-Phellandrene | 443160 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| BDNF | ANON2; BULN2 | 11p14.1 | 29859319 |
| CCR5 | CC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; CMKBR5; IDDM22 | 3p21.31 | 31557508 |
| CEBPA | C/EBP-alpha; CEBP | 19q13.11 | 29141998 |
| CHRNA7 | CHRNA7-2; NACHRA7 | 15q13.3 | 31560162 |
| EGR3 | EGR-3; PILOT | 8p21.3 | 31858986 |
| MECP2 | AUTSX3; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT | Xq28 | 29859319 |
| PARP1 | ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1 | 1q42.12 | 31384538 |
| PPARG | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma | 3p25.2 | 29141998 |
| SIGMAR1 | ALS16; DSMA2; OPRS1; SIG-1R; SR-BP; SR-BP1; SRBP; hSigmaR1; sigma1R | 9p13.3 | 31560162 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Aging | phenotype | 24932939 |
| Alzheimer's Disease | disease | 31560162 |
| Autistic Disorder | disease | 27752075 |
| Child Development Disorders, Pervasive | group | 27752075 |
| Cocaine-Related Disorders | group | 30166527 |
| Diabetes Mellitus | group | 25411288 |
| Down Syndrome | disease | 24932939 |
| Glucose tolerance test | phenotype | 25411288 |
| Insulin Resistance | phenotype | 25411288 |
| Language Development Disorders | group | 27752075 |
