1. 药材主信息
| 中文名称: | 叉蕊薯蓣 |
| 英文名称: | Collett Yam |
| 拉丁名称: | Dioscorea collettii |
| 使用部位: | rhizome |
| 功用: | To dispel wind and disinhibit damp, free network vessels and relieve pain, clear heat and resolve toxin. |
| 适用症: | Wind-damp impediment pain, hypertonicity and numbness, qi stagnation stomachache, damp-heat jaundice, white turbidity, strangury with pain, leukorrhea, knocks and falls, damp sore with swelling toxin, wind papules, eczema, poisonous snake bite. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 19057-60-4 | - | (2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[(1S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol | 159860 |
| 549-08-6 | - | (4aR)-3,4,4a,5,18,19-Hexahydro-9,21,22,26-tetramethoxy-4-methyl-2H-1,24:12,15-dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline | 5317122 |
| 105454-04-4 | 7-表紫杉醇 | 7-epi-Taxol | 184492 |
| 1143-54-0 | - | Deoxynupharidine | 442525 |
| 530-53-0 | 脱氧鸭嘴花碱酮 | Deoxyvasicinone | 68261 |
| 470-03-1 | - | Episarsasapogenin | 12304430 |
| 500-62-9 | 麻醉椒素 | Yangonin | 5281575 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 22461009 |
| MAPK14 | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA | 6p21.31 | 21195543 |
| MAPK3 | ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK | 16p11.2 | 22461009 |
| PDCD1 | CD279; PD-1; PD1; SLEB2; hPD-1; hPD-l; hSLE1 | 2q37.3 | 30305604 |
| PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | 1q31.1 | 21195543 |
| RPL17 | L17; PD-1; RPL23 | 18q21.1 | 30305604 |
| RPL17-C18orf32 | PD-1; RPL17 | 18q21.1 | 30305604 |
| TNFRSF10B | CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9 | 8p21.3 | 21195543 |
