1. 药材主信息
| 中文名称: | 苍耳子 |
| 英文名称: | fruit of Siberian Cockleblur |
| 拉丁名称: | Fructus Xanthii sibirici |
| 使用部位: | - |
| 功用: | To dispel wind and damp, and to relieve nasal obstruction. |
| 适用症: | 1. Lowering blood sugar, with similar mechanism as phenethyl biguanide ( DBI ). 2. Its chief poisonous component is rhamnose. The toxic effects in rats, guinea-pigs and rabbits by different routes of administration are similar. LD50 is 0.93g/kg in mice. |
| 毒副作用: | Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 506-30-9 | 花生酸 | - | 10467 |
| 112-31-2 | 癸醛 | - | 8175 |
| 13877-91-3 | 罗勒烯 | - | 5281553 |
| 112-31-2 | 癸醛 | - | 8175 |
| 498-15-7 | (1S)-(+)-3-蒈烯 | (+)-3-Carene | 443156 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 7785-53-7 | - | (+)-alpha-Terpineol | 442501 |
| 489-39-4 | (+)-Aromadendrene | (+)-Aromadendrene | 11095734 |
| 118916-57-7 | 右旋蛇菰宁 | (+)-Balanophonin | 23252258 |
| 7632-16-8 | - | (+)-cis-Carveol | 443177 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB1 | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 | 7q21.12 | 27058921 |
| ABCB1 | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 | 7q21.12 | 28958806 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC1 | ABC29; ABCC; GS-X; MRP; MRP1 | 16p13.11 | 28958806 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 28958806 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinogenesis | phenotype | 25047426 |
| Chemical and Drug Induced Liver Injury | disease | 28958806 |
| Colonic Neoplasms | group | 25047426 |
| Diabetes | disease | 28707095 |
| Diabetes | disease | 31166006 |
| Esophageal Neoplasms | group | 26603620 |
| Head and Neck Neoplasms | group | 24157255 |
| Hyperglycemia | disease | 23471488 |
| Hyperglycemia | disease | 28707095 |
| Liver diseases | group | 24107776 |
