1. 药材主信息
| 中文名称: | 蝙蝠葛根 |
| 英文名称: | Asiatic Moonseed Root |
| 拉丁名称: | Menispermum dauricum |
| 使用部位: | rhizome |
| 功用: | To clear heat and resolve toxin, disperse swelling and relieve pain, disinhibit damp. |
| 适用症: | Swelling pain in throat, lung heat cough, epidemic parotitis, diarrhea, jaundice, wind-damp impediment pain, swelling pain from hemorrhoids, snake or insect bites. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 25342-82-9 | - | (6As)-11-hydroxy-1,2,10-trimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinolinium | 161487 |
| 18145-26-1 | Acutumidine | Acutumidine | 442840 |
| 30984-80-6 | - | Dauricinoline | 71463990 |
| 2831-75-6 | 蝙蝠葛诺林碱 | Daurinoline | 12309092 |
| 70553-76-3 | 蝙蝠葛苏林碱 | Daurisoline | 51106 |
| 16562-13-3 | 左旋千金藤啶碱 | l-Stepholidine | 6917970 |
| 83287-02-9 | 蝙蝠葛波酚碱 | Menisporphine | 150032 |
| 6514-05-2 | - | N-Methylcorydaldine | 303906 |
| 139-85-5 | 原儿茶醛 | Protocatechualdehyde | 8768 |
| 115-53-7 | 青藤碱 | Sinomenine | 5459308 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AHR | RP85; bHLHe76 | 7p21.1 | 30674869 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 28901537 |
| BECN1 | ATG6; VPS30; beclin1 | 17q21.31 | 24625982 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 24625982 |
| CBL | C-CBL; CBL2; FRA11B; NSLL; RNF55 | 11q23.3 | 30674869 |
| CCND1 | BCL1; D11S287E; PRAD1; U21B31 | 11q13.3 | 29605511 |
| Cd24a | Cd24; HSA; Ly-52; nectadrin | 10 B2|10 23.01 cM | 24212809 |
| CD44 | CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1 | 11p13 | 24212809 |
| CDKN1A | CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 | 6p21.2 | 29605511 |
| CDKN1B | CDKN4; KIP1; MEN1B; MEN4; P27KIP1 | 12p13.1 | 29605511 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 26795599 |
| Arthritis | disease | 30674869 |
| Arthritis, Experimental | disease | 29401630 |
| Bone Resorption | phenotype | 30674869 |
| Bone Resorption | phenotype | 29401630 |
| Brain Edema | phenotype | 27724964 |
| Brain Ischemia | disease | 21585344 |
| Cerebral Infarction | disease | 27724964 |
| Encephalitis | disease | 27724964 |
| Epilepsy | disease | 29776417 |
