科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 白首乌
英文名称: Bunge Swallowwort Equivalent plant: Cynanchum auri
拉丁名称: Cynanchum bungei
使用部位: tuberoid
功用: To supplement lung and boost kidney, strengthen sinews and bones, boost essence and blood, fortify spleen and disperse food, resolve toxin and cure sores.
适用症: Aching in lumbus and knees, impotence and emission, dizziness and tinnitus, palpitation and insomnia, inappetence, child gan sore, postpartum scant milk, swelling toxin of sore and welling abscess, poisonous snake bite.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
6869-50-7 - 14beta,17alpha-Pregn-5-en-20-one, 3beta,8,12beta,14-tetrahydroxy- 12311278
149475-52-5 - Bungeiside A 127685
149561-88-6 - Bungeiside B 127689
149475-53-6 - Bungeiside C 127686
149475-54-7 - Bungeiside D 127687
134-01-0 - CID 441773 441773
3513-04-0 去酰蓟萝摩苷元 Deacylmetaplexigenin 21633061
80931-34-6 - Kigelinone 442752
27526-87-0 - Penupogenin 56841085
18607-76-6 - Sarcostin 46173994

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
BCL2 Bcl-2; PPP1R50 18q21.33 27184666
CASP3 CPP32; CPP32B; SCA-1 4q35.1 27184666
CASP7 CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3 10q25.3 27184666
CASP9 APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 1p36.21 27184666
PARP1 ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1 1q42.12 27184666

4. 相关疾病

疾病名称 疾病类型 参考文献
Brain Neoplasms group 27184666
Glioma disease 27184666