1. 药材主信息
| 中文名称: | 白刺花 |
| 英文名称: | Vetchleaf Sophora |
| 拉丁名称: | Sophora viciifolia |
| 使用部位: | root |
| 功用: | To clear heat and disinhibit throat, cool blood and disperse swelling. |
| 适用症: | Swelling pain in throat, cough, hepatitis, dysentery, strangury syndrome, edema, hematuria, nosebleed(epistaxis), hematochezia. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 3153-73-9 | 松风草内酯 | 7-Methoxy-8-(7-methoxy-2-oxochromen-6-yl)chromen-2-one | 5319307 |
| 520-34-3 | 香叶木素 | Diosmetin | 5281612 |
| 520-27-4 | 地奥司明 | Diosmin | 5281613 |
| 519-02-8 | 苦参碱 | Matrine | 91466 |
| 483-89-6 | - | Oxynarcotine | 5320347 |
| 50-56-6 | Oxytocin | Oxytocin | 439302 |
| 145572-44-7 | 槐果碱 | Sophocarpine | 115269 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 30825187 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26945965 |
| BAX | BCL2L4 | 19q13.33 | 21714853 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21714853 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30822359 |
| BIRC7 | KIAP; LIVIN; ML-IAP; MLIAP; RNF50 | 20q13.33 | 21714853 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21714853 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 26945965 |
| CYCS | CYC; HCS; THC4 | 7p15.3 | 21714853 |
| GABPA | E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07 | 21q21.3 | 30825187 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute Lung Injury | disease | 26361726 |
| Head and Neck Neoplasms | group | 28571917 |
| Inflammation | phenotype | 26361726 |
| Liver neoplasms | group | 26945965 |
| Pancreatic Neoplasm | disease | 21714853 |
| Psoriasis | disease | 30822359 |
| Psoriasis | disease | 28112799 |
