科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 靶点主信息

NCBI Gene id: 6558
Gene_name: SLC12A2
Gene alias: BSC; BSC2; NKCC1; PPP1R141
Map location: 5q23.3
Type of gene: protein-coding
Description: solute carrier family 12 member 2
OMIM_id: 600840
HGNC_id: 10911
Ensembl_id: ENSG00000064651

2. 相关药材

中文名称 英文名称 拉丁文名称
布渣叶 Microctis Folium -
长瓣金莲花 Langpetal Globeflower Trollius macropetalus
单叶蔓荆 Simpleleaf Shrub Chastetree Vitex rotundifolia [Syn. Vitex trifollia var. simp
单叶蔓荆子 Simpleleaf Shrub Chastetree Fruit Vitex rotundifolia [Syn. Vitex trifollia var. simp
灯心草 pith of Common Rush Medulla Junci
丁香 Clove Flos Caryophylli
翻白草 all-grass of discolor cinquefoil Herba Potentillae Discoloris
浮萍 all-grass of Common Ducksmeat Herba Spirodelae
甘草 Root of Ural Licorice Radix Glycyrrhizae
甘肃山楂 Kansu Hawthorn Crataegus kansuensis

3. 相关成分

CAS号 中文名称 英文名称 参考文献
4368-28-9 - (1R,5R,6R,7R,9S,11S,13S,14R)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.17,11.01,6]tetradec-3-ene-5,9,12,13,14-pentol 139251219
3681-93-4 牡荆苷;牡荆素 Vitexin 5280441

4. 相关疾病

疾病名称 疾病类型 参考文献
Bladder pain syndrome disease 30157135
Blood Pressure phenotype 23570977
Brain Waves phenotype 30228120
Cardiomegaly phenotype 23570977
Chronic pain phenotype 30648289
Epilepsy disease 29925377
Epilepsy, Temporal Lobe disease 28860087
Gliosis phenotype 24740847
Heart failure disease 25424392
Heart failure disease 23570977