1. 药材主信息
| 中文名称: | 紫金牛 |
| 英文名称: | Japanese Ardisia |
| 拉丁名称: | Ardisia japonica |
| 使用部位: | stem-leaf |
| 功用: | To suppress cough, dispel phlegm, quicken blood, disinhibit urine, resolve toxin. |
| 适用症: | Chronic trachitis, hepatitis, acute nephritis, chronic nephritis, tuberculosis and hemoptysis, blood ejection, dysentery, hypertension, mounting qi, taxation damage and strength desertion, aching sinews and bones, toxin swelling. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 1617-84-1 | 6-O-甲基梓醇 | 6-O-methylcatalpol | 53248734 |
| 6466-94-0 | - | Bauerenol | 111220 |
| 477-90-7 | 岩白菜素 | Bergenin | 66065 |
| 550-24-3 | 恩贝酸 | Embelin | 3218 |
| 119-36-8 | 水杨酸甲酯 | Methyl Salicylate | 4133 |
| 17912-87-7 | 杨梅苷 | Myricitrin | 5281673 |
| 123442-26-2 | - | Myricomplanoside | 5487255 |
| 522-12-3 | 槲皮苷 | Quercitrin | 5280459 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27017346 |
| ARG1 | - | 6q23.2 | 30377563 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21565443 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21709246 |
| CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | 16q22.1 | 27017346 |
| CEBPB | C/EBP-beta; IL6DBP; NF-IL6; TCF5 | 20q13.13 | 30377563 |
| GPR84 | EX33; GPCR4 | 12q13.13 | 29471103 |
| IL17A | CTLA-8; CTLA8; IL-17; IL-17A; IL17 | 6p12.2 | 25128650 |
| IL6 | BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 | 7p15.3 | 25128650 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 27017346 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Atherosclerosis | disease | 27017346 |
| Brain Ischemia | disease | 21709246 |
| Carcinoma | group | 25974735 |
| Carcinoma, Papillary | disease | 25974735 |
| Charcot-Marie-Tooth Disease | disease | 31695036 |
| Inflammation | phenotype | 25128650 |
| Ischemia | phenotype | 27017346 |
| Multiple Myeloma | disease | 21565443 |
| Pancreatic Neoplasm | disease | 25128650 |
| Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | disease | 29170254 |
