1. 药材主信息
| 中文名称: | 肿节风 |
| 英文名称: | all-grass of Glabrous sarcandra |
| 拉丁名称: | Herba Sarcatidrae |
| 使用部位: | - |
| 功用: | 1. Inhibiting the growth of Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhosa and various Shigella dysenteriae in vitro. 2. Nonspecfic anti-inflammatory and promoting the repair of gastric ulcer. 3. Its volatile oil and flavones inhibit sa |
| 适用症: | 1. To clear heat and toxic material. For carbuncle due to intensive heat, aphthae, gingivitis, dysentery, filariasis, etc. 2. To promote blood circulation and remove blood stasis, expel wind and dredge channels. For trauma, rheumatism, stomachache. Recent |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 480-37-5 | - | (2R)-5-hydroxy-7-methoxy-2-phenyl-2,3-dihydrochromen-4-one | 6950539 |
| 99-96-7 | 对羟基苯甲酸 | 4-Hydroxybenzoic acid | 135 |
| 73069-14-4 | 白术内酯II | Atractylenolide II | 14448070 |
| 73030-71-4 | 白术内酯III | Atractylenolide III | 155948 |
| 112-85-6 | 二十二烷酸 | Behenic Acid | 8215 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 331-39-5 | 咖啡酸 | Caffeic Acid | 689043 |
| 66395-02-6 | - | Chloranthalactone A | 333361 |
| 131-11-3 | - | Dimethyl Phthalate | 8554 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKR1B1 | ADR; ALDR1; ALR2; AR | 7q33 | 21712449 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20840540 |
| BAX | BCL2L4 | 19q13.33 | 30326282 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30326282 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 30326282 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 30326282 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 30326282 |
| CATSPER1 | CATSPER; SPGF7 | 11q13.1 | 28507119 |
| CEBPA | C/EBP-alpha; CEBP | 19q13.11 | 29141998 |
| CTBP1 | BARS; HADDTS | 4p16.3 | 29988033 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Esophageal Neoplasms | group | 26603620 |
| Liver neoplasms | group | 25101566 |
| Lung Neoplasms | group | 29988033 |
| Melanoma, Experimental | disease | 20840540 |
| Neoplasm Metastasis | phenotype | 20840540 |
| Obesity | disease | 28049156 |
