1. 药材主信息
| 中文名称: | 栀子 |
| 英文名称: | fruit of Cape Jasmine |
| 拉丁名称: | Fructus Gardeniae |
| 使用部位: | ripe fruit |
| 功用: | 1. To clear heat and reduce fire; 2. To cool blood and release toxins; 3. To eliminate dampness |
| 适用症: | Acute icterohepatitis, febrile diseases, vexation, melancholia, restlessness, stagnation of damp-heat in liver and gall, fever, jaundice, short voidings of reddish urine, blood ejection, spontaneous external bleeding, dysentery with hematochezia and hematuria. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 1119-38-6 | 反-(+)-橙花叔醇 | (3S,6E)-Nerolidol | 5281525 |
| 189148-81-0 | - | (4S)-4-[(I(2)-D-Glucopyranosyloxy)methyl]-3,5,5-trimethyl-2-cyclohexen-1-one | 95789921 |
| 533-73-3 | - | 1,2,4-Benzenetriol | 10787 |
| 66851-47-6 | - | 1,2-Benzenedi(carboxylic-14C)acid, dibutyl ester | 171810 |
| 1182-34-9 | 1,4-二咖啡酰奎宁酸 | 1,4-Dicaffeoylquinic acid | 12358846 |
| 2363-88-4 | 反式-2,4-癸二烯醛 | 2,4-Decadienal | 5283349 |
| 1072-05-5 | - | 2,6-Dimethylheptane | 14069 |
| 2548-87-0 | E-2-辛烯醛 | 2-Octenal | 5283324 |
| 3777-69-3 | 2-戊基呋喃 | 2-Pentylfuran | 19602 |
| 53350-26-8 | 3',4',5',5,7-五甲氧基黄酮 | 3',4',5',5,7-Pentamethoxyflavone | 493376 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| AHR | RP85; bHLHe76 | 7p21.1 | 26515162 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31678208 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25950476 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31406198 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Aging | phenotype | 24932939 |
| Alzheimer's Disease | disease | 31560162 |
| Asthma | disease | 27185659 |
| Autoimmune Diseases | group | 26996065 |
| Blood Pressure | phenotype | 28143892 |
| Body Weight | phenotype | 24559844 |
| Bronchial Hyperreactivity | disease | 27185659 |
| Carcinoma, Pancreatic Ductal | disease | 28962872 |
| Cardiac Hypertrophy | phenotype | 26845648 |
