1. 药材主信息
| 中文名称: | 炙马钱子 |
| 英文名称: | Nux Vomica |
| 拉丁名称: | Semen Strychni Praeparata |
| 使用部位: | Strychnos nux-vomica L.;Strychnos pierriana A. W. Hill. |
| 功用: | Treatment of protracted arthritis, rheumatoid arthralgia, numbness and paralysis, sequala of poliomyelitis, traumatic injury, boils and sores. |
| 适用症: | Treatment of protracted arthritis, rheumatoid arthralgia, numbness and paralysis, sequala of poliomyelitis, traumatic injury, boils and sores. |
| 毒副作用: | Extremely Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 63428-84-2 | 马钱子碱 | Brucine | 442021 |
| 35354-74-6 | 和厚朴酚 | Honokiol | 72303 |
| 6801-40-7 | 木兰箭毒碱 | Magnocurarine | 53266 |
| 528-43-8 | 厚朴酚 | Magnolol | 72300 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ADAMTS4 | ADAMTS-2; ADAMTS-4; ADMP-1 | 1q23.3 | 29649568 |
| ADAMTS5 | ADAM-TS 11; ADAM-TS 5; ADAM-TS5; ADAMTS-11; ADAMTS-5; ADAMTS11; ADMP-2 | 21q21.3 | 29649568 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26454217 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27940017 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 30587839 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21757288 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31905887 |
| BAX | BCL2L4 | 19q13.33 | 22259050 |
| BAX | BCL2L4 | 19q13.33 | 29649568 |
| BAX | BCL2L4 | 19q13.33 | 30587839 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute Lung Injury | disease | 21279327 |
| Brain Edema | phenotype | 30597199 |
| Brain Ischemia | disease | 30597199 |
| Brain Neoplasms | group | 22259050 |
| Carcinoma, Ehrlich Tumor | disease | 23348691 |
| Cardiomegaly | phenotype | 25871545 |
| Cerebral Hemorrhage | phenotype | 30597199 |
| Endotoxemia | phenotype | 21279327 |
| Fibrosis | phenotype | 21265825 |
| Glioblastoma | disease | 30587839 |
