1. 药材主信息
| 中文名称: | 樟脑 |
| 英文名称: | Camphorar |
| 拉丁名称: | Camphora |
| 使用部位: | Cinnamomum camphora (L.) Presi |
| 功用: | For coma of sthenic type, especially those due to affection of filthy and turbid substance. External use for scabies, tinea, skin infection, prurigo, trauma, toothache; oral use for vomiting and diarrhea of cold-dampness type, chest pain, abdominal pain of stomach-cold origin, dyspepsia with abdominal distending pain. |
| 适用症: | 1. Local application to the skin exerts a mild local anesthetic effect. 2. Oral use in small amount produces a feeling of warmth and comfort in the stomach, while in large dose causes irritating and leads to nausea and vomiting. 3. Stimulating the central nervous system, and also non-selectively the respiration. Large dose may cause convulsion. |
| 毒副作用: | Extremely Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 99-83-2 | 水芹烯 | - | 7460 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 7785-53-7 | - | (+)-alpha-Terpineol | 442501 |
| 652971-46-5 | (3R,4S)-4-苯基吡咯烷-3-羧酸 | (3R,4S)-4-Phenylpyrrolidine-3-carboxylic acid | 51051667 |
| 17430-12-5 | - | (3R,6E)-nerolidol | 11241545 |
| 5715-23-1 | 3,4-二甲基环己醇(异构体的混合物) | 3,4-Dimethylcyclohexanol | 97960 |
| 562-74-3 | 4-松油醇 | 4-Terpineol, (+/-)- | 11230 |
| 104-46-1 | 反式茴香脑 | Anethole | 637563 |
| 104-46-1 | 反式茴香脑 | Anethole | 637563 |
| 100-52-7 | 苯甲醛 | Benzaldehyde | 240 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31678208 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| CCL3 | G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3 | 17q12 | 25784697 |
| CD1A | CD1; FCB6; HTA1; R4; T6 | 1q23.1 | 25784697 |
| CD80 | B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7 | 3q13.33 | 25784697 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| HIV Infections | group | 22677126 |
| Liver diseases | group | 24107776 |
| Multiple Myeloma | disease | 25697480 |
| Multiple Myeloma | disease | 23044853 |
| Pain | phenotype | 28396565 |
