1. 药材主信息
| 中文名称: | 泽泻 |
| 英文名称: | rhizome of Oriental Waterplantain |
| 拉丁名称: | Rhizoma Alismatis |
| 使用部位: | tuber |
| 功用: | To cause diuresis, and to remove damp-heat. To transform dampness and promote water metabolism. |
| 适用症: | Hyperlipemia, inhibited urination, heat strangury with inhibited pain, edema distention fullness, diarrhea, phlegm-rheum dizziness, emission. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 32899-41-5 | L-ALPHA-PALMITIN | 1-Hexadecanoyl-sn-glycerol | 3084463 |
| 67-47-0 | 5-羟甲基糠醛 | 5-Hydroxymethylfurfural | 237332 |
| 18674-16-3 | 泽泻醇A-24-醋酸酯;24-乙酰泽泻醇A; | alisol A 24-acetate | 76336194 |
| 26575-93-9 | 23-乙酰泽泻醇C | alisol C 23-acetate | 14036813 |
| 155301-58-9 | 泽泻醇 E 23-醋酸酯 | Alisol E 23-acetate | 101661272 |
| 155521-45-2 | 泽泻醇F | alisol F | 76310822 |
| 10489-79-9 | - | alpha-D-Fructofuranose | 11105942 |
| 2277-28-3 | - | alpha-Glyceryl linoleate | 6436630 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 62-49-7 | 2-羟基-N,N,N-三甲基乙铵 | Choline | 305 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
| ALPP | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 | 2q37.1 | 25832436 |
| ASRGL1 | ALP; ALP1; CRASH | 11q12.3 | 25832436 |
| ATHS | ALP | 19p13.3-p13.2 | 25832436 |
| ATRNL1 | ALP; bA338L11.1; bA454H24.1 | 10q25.3 | 25832436 |
| BGLAP | BGP; OC; OCN | 1q22 | 25832436 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 30897821 |
| CCL27 | ALP; CTACK; CTAK; ESKINE; ILC; PESKY; SCYA27 | 9p13.3 | 25832436 |
| CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | 16q22.1 | 24157255 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Aging | phenotype | 24932939 |
| Alzheimer's Disease | disease | 31560162 |
| Down Syndrome | disease | 24932939 |
| Head and Neck Neoplasms | group | 24157255 |
| Liver neoplasms | group | 23848338 |
| Nasopharyngeal carcinoma | disease | 31731581 |
| Osteoporosis | disease | 25832436 |
| Trisomy | group | 24932939 |
