1. 药材主信息
| 中文名称: | 云南羌活 |
| 英文名称: | Yunnan Pleurospermum |
| 拉丁名称: | Pleurospermum rivulorum |
| 使用部位: | root |
| 功用: | To dispel wind and eliminate damp, free network vessels and relieve pain. |
| 适用症: | Wind-cold common cold, wind-cold-damp impediment, hypertonicity of sinews and vessels, headache, pain in stomach duct and abdomen. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 139079-42-8 | 独活属醇 | (-)-Heraclenol | 40429858 |
| 13710-70-8 | 印度榅桲素 | 2-(2-Hydroxypropan-2-yl)-2,3-dihydrofuro[3,2-g]chromen-7-one | 604512 |
| 495-30-7 | 异紫花前胡苷 | Ammijin | 216283 |
| 61825-98-7 | 西贝母碱 | Imperialine | 442977 |
| 53319-52-1 | 异栓翅芹醇 | Isogosferol | 148619 |
| 26833-86-3 | - | Isoharringtonine | 73492 |
| 298-81-7 | 花椒毒素 | Methoxsalen | 4114 |
| 482-44-0 | 欧前胡素 | Pentosalen | 10212 |
| 2009-24-7 | 花椒毒酚 | Xanthotoxol | 65090 |
| 7437-55-0 | 8-香叶草氧基补骨脂素 | Xanthotoxol geranyl ether | 5317564 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| BAK1 | BAK; BAK-LIKE; BCL2L7; CDN1 | 6p21.31 | 24680709 |
| BAX | BCL2L4 | 19q13.33 | 24680709 |
| CYP3A4 | CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450C3; P450PCN1 | 7q22.1 | 29945292 |
| IL10 | CSIF; GVHDS; IL-10; IL10A; TGIF | 1q32.1 | 27185659 |
| MCL1 | BCL2L3; EAT; MCL1-ES; MCL1L; MCL1S; Mcl-1; TM; bcl2-L-3; mcl1/EAT | 1q21.2 | 24680709 |
| NFKB1 | CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB | 4q24 | 29945292 |
| NR1I2 | BXR; ONR1; PAR; PAR1; PAR2; PARq; PRR; PXR; SAR; SXR | 3q13.33 | 29945292 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Asthma | disease | 27185659 |
| Bronchial Hyperreactivity | disease | 27185659 |
| Colitis | disease | 29945292 |
| Liver neoplasms | group | 24680709 |
