1. 药材主信息
| 中文名称: | 芫花 |
| 英文名称: | flower bud of Lilac Daphne |
| 拉丁名称: | Flos Genkwa |
| 使用部位: | bud |
| 功用: | 1. To transform water and stop cough; 2. To resolve phlegm and stop cough; 3. To kill worms |
| 适用症: | Edema, ascites, hydrothorax, cough with profuse phlegm, chronic bronchitis, malaria, scalp infection, infection of skin, tinea capitis, neurodermatitis, induce abortion, toothache. |
| 毒副作用: | Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 24587-53-9 | - | (S)-1-Octen-3-ol | 2724898 |
| 95-63-6 | - | 1,2,4-Trimethylbenzene | 7247 |
| 620-14-4 | 3-乙基甲苯 | 3-Ethyltoluene | 12100 |
| 123-08-0 | 对羟基苯甲醛 | 4-Hydroxybenzaldehyde | 126 |
| 29080-58-8 | 7,3’,4’-三-O-甲基毛地黄黄酮 | 5-Hydroxy-3',4',7-trimethoxyflavone | 5272653 |
| 20243-59-8 | 羟基芫花素 | 7-O-Methylluteolin | 5318214 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 100-52-7 | 苯甲醛 | Benzaldehyde | 240 |
| 65-85-0 | 苯甲酸 | Benzoic Acid | 243 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 29235094 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 29235094 |
| ACACA | ACAC; ACACAD; ACC; ACC1; ACCA | 17q12 | 30630510 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 23684930 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21871133 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 21871133 |
| BNIP3 | NIP3 | 10q26.3 | 28838842 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 26418626 |
| CAT | - | 11p13 | 29179721 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Alzheimer's Disease | disease | 30447302 |
| Blood Pressure | phenotype | 28143892 |
| Cholestasis | disease | 29235094 |
| Colitis | disease | 22677088 |
| Crohn Disease | disease | 22677088 |
| Electrocardiography | phenotype | 23058930 |
| Enterovirus Infections | group | 30254193 |
| Epstein-Barr Virus Infections | group | 28056971 |
| Fibrosis | phenotype | 28143892 |
