1. 药材主信息
| 中文名称: | 禹州漏芦 |
| 英文名称: | Globethistle Root |
| 拉丁名称: | Radix Echinopsis |
| 使用部位: | - |
| 功用: | To remove heat and counteract toxicity, drainage of pus, stanch bleeding, to cure sores and carbuncles, increase the secretion of milk. |
| 适用症: | Treatment of sores, carbuncles, swelling and pain due to mastitis, galactostasis, tuberculosis of lypmhaden, pyogenic infection. It can be used as antheimintic. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 22527-23-7 | - | (+)-alpha-Santalene | 12315252 |
| 89-80-5 | - | (+)-Menthone | 443159 |
| 3515-18-2 | - | 1-(5-Thiophen-2-ylthiophen-2-yl)ethanone | 606422 |
| 1081-34-1 | α-三联噻吩 | 2,2':5',2''-Terthiophene | 65067 |
| 1134-61-8 | - | 5-(3-Buten-1-ynyl)-2,2'-bithiophene | 70813 |
| 1137-87-7 | - | 5-(4-Hydroxybut-1-ynyl)-2,2'-bithiophene | 440357 |
| 18252-46-5 | - | alpha-CIS-BERGAMOTENE | 6429303 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 3691-11-0 | - | Delta-Guaiene | 94275 |
| 84-74-2 | 邻苯二甲酸二丁酯（植物提取） | Dibutyl Phthalate | 3026 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25047426 |
| AURKA | AIK; ARK1; AURA; BTAK; PPP1R47; STK15; STK6; STK7 | 20q13.2 | 25047426 |
| BAX | BCL2L4 | 19q13.33 | 25047426 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 25047426 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 27714757 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 25047426 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 25047426 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 25047426 |
| CXCL1 | FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 | 4q13.3 | 25281414 |
| CYC1 | MC3DN6; UQCR4 | 8q24.3 | 25047426 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinogenesis | phenotype | 25047426 |
| Colitis | disease | 25281414 |
| Colonic Neoplasms | group | 25047426 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Liver Failure, Acute | disease | 27714757 |
| Obesity | disease | 28049156 |
| Obesity | disease | 29160087 |
| Ventricular Remodeling | phenotype | 26185015 |
