1. 药材主信息
| 中文名称: | 余甘子 |
| 英文名称: | Emblic Leafflower Fruit |
| 拉丁名称: | Fructus Phyllanthi |
| 使用部位: | - |
| 功用: | To remove heat from blood, to promote digestion and the production of body fluid, and to relieve cough. |
| 适用症: | Treatment of heat in the blood and blood stasis, liver and gall bladder diseases, dyspepsia, abdominal pain, cough, sore throat, dryness of the mouth. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 24808-04-6 | (-)-表阿夫儿茶精 | (-)-Epiafzelechin | 443639 |
| 1257-08-5 | 表儿茶素没食子酸酯 | (-)-Epicatechin gallate | 107905 |
| 614-75-5 | 2-羟基苯乙酸 | 2-Hydroxyphenylacetic acid | 11970 |
| 480-10-4 | 紫云英苷 | Astragalin | 5282102 |
| 638-97-1 | - | beta-Amyrone | 12306160 |
| 13405-60-2 | β-Glucogalin | beta-Glucogallin | 124021 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 334-48-5 | 正癸酸 | Capric Acid | 2969 |
| 23725-05-5 | 诃子次酸 | Chebulic acid | 71308174 |
| 154-23-4 | (+)-儿茶素 | Cianidanol | 9064 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 29235094 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 29235094 |
| ACACA | ACAC; ACACAD; ACC; ACC1; ACCA | 17q12 | 30630510 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 23684930 |
| BNIP3 | NIP3 | 10q26.3 | 28838842 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 26418626 |
| CYCS | CYC; HCS; THC4 | 7p15.3 | 26418626 |
| CYP2J2 | CPJ2; CYPIIJ2 | 1p32.1 | 24216999 |
| CYP4F2 | CPF2 | 19p13.12 | 24216999 |
| CYP7A1 | CP7A; CYP7; CYPVII | 8q12.1 | 29235094 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 30447302 |
| Cholestasis | disease | 29235094 |
| Colitis | disease | 22677088 |
| Crohn Disease | disease | 22677088 |
| Diabetes | disease | 28707095 |
| Electrocardiography | phenotype | 23058930 |
| Enterovirus Infections | group | 30254193 |
| Helicobacter Infections | group | 29566160 |
| Hyperglycemia | disease | 28707095 |
| Hyperlipidemia | disease | 23058930 |