科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 茵陈
英文名称: Virgate Wormwood Herb
拉丁名称: Herba Artemisiae Scopariae
使用部位: -
功用: To remove damp-heat and relieve jaundice.
适用症: 1. Its decoction or its volatile oil, and active components such as chlorogenic acid, caffeic acid and hydroxyacetophenone are chologogues.2. Protecting the liver of experimental animals from the damage of CCl4.3. Decreasing the level of blood lipids and alleviating artherosclerosis and lipidosis in rabbits.4. Increasing the coronary flow of rabbits in vitro.5. Its volatile oil inhibits the growth of Shigella dysenteriae, Hemolytic streptococcus and various dermatomyces in vitro.6. Anticoagulative.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
7785-53-7 - (+)-alpha-Terpineol 442501
20296-50-8 - (-)-3-Carene 442461
20296-50-8 - (-)-3-Carene 442461
582-24-1 2-羟基苯乙酮 2-Hydroxyacetophenone 68490
821-55-6 2-壬酮 2-Nonanone 13187
99-93-4 4'-羟基苯乙酮 4'-Hydroxyacetophenone 7469
61854-36-2 Demethoxycapillarisin 6-Demethoxycapillarisin 5316511
531-59-9 7-甲氧基香豆素 7-Methoxycoumarin 10748
83162-82-7 - Arcapillin 158311
37971-69-0 7-O-Methylaromadendrin Aromadendrin 7-methyl ether 181132

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
AGT ANHU; SERPINA8; hFLT1 1q42.2 23127783
CAMK2G CAMK; CAMK-II; CAMKG; MRD59 10q22.2 31138329
CASP12 CASP-12; CASP12P1 11q22.3 24840537
CASP3 CPP32; CPP32B; SCA-1 4q35.1 21951288
CASP8 ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 2q33.1 21951288
CASP9 APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 1p36.21 24840537
CAT - 11p13 24559844
CCNA2 CCN1; CCNA 4q27 29271007
CCNB1 CCNB 5q13.2 31590241
CCND1 BCL1; D11S287E; PRAD1; U21B31 11q13.3 29271007

4. 相关疾病