1. 药材主信息
| 中文名称: | 益母草 |
| 英文名称: | motherwort |
| 拉丁名称: | Herba Leonuri |
| 使用部位: | aerial parts |
| 功用: | 1. To promote blood circulation to remove blood stasis, regulate menstruation and relieve metrorrhagia. 2. To promote diuresis and relieve edema. 3. To clear heat and toxic materials. 4. Lower blood pressure. |
| 适用症: | Menstrual disorder, dysmenorrhea, amenorrhea, postpartum bleeding, persistent flow of lochia, edema, scant urine with edema, acute nephritis with edema. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 15233-65-5 | 2,6-二甲氧基对苯二酚 | 2,6-Dimethoxyhydroquinone | 96038 |
| 7541-49-3 | 叶绿醇 | 3,7,11,15-Tetramethyl-2-hexadecen-1-OL | 5366244 |
| 17581-95-2 | - | 4-Guanidino-1-butanol | 5317848 |
| 463-00-3 | 4-胍基丁酸 | 4-Guanidinobutyric acid | 500 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 506-32-1 | 花生四烯酸 | Arachidonic Acid | 444899 |
| 13744-15-5 | - | beta-Cubebene | 93081 |
| 1139-30-6 | 石竹素 | Caryophyllene oxide | 1742210 |
| 628-97-7 | 棕榈酸乙酯 | Ethyl palmitate | 12366 |
| 1135-24-6 | 阿魏酸 | Ferulic acid | 445858 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 23127783 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24486741 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21871133 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 21871133 |
| CAMK2G | CAMK; CAMK-II; CAMKG; MRD59 | 10q22.2 | 31138329 |
| CASP12 | CASP-12; CASP12P1 | 11q22.3 | 24840537 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 22310289 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21951288 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Alzheimer's Disease | disease | 30447302 |
| Blood Pressure | phenotype | 28143892 |
| Blood Pressure | phenotype | 25076013 |
| Colitis | disease | 25281414 |
| Colorectal Neoplasms | group | 23824743 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Epstein-Barr Virus Infections | group | 28056971 |
