1. 药材主信息
| 中文名称: | 羊角坳子 |
| 英文名称: | Divaricate Strophanthus Seed |
| 拉丁名称: | Strophanthus divaricatus |
| 使用部位: | seed |
| 功用: | To quicken blood and disperse swelling, strengthen heart, kill worms and relieve itch. |
| 适用症: | Wind-damp, scab and lichen, knocks and falls, swelling of sores, cardiac failure, rheumatic arthritis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 17184-21-3 | 常春藤皂苷元-3-O-α-L-吡喃阿拉伯糖苷 | Cauloside A | 441928 |
| 6869-51-8 | - | Cuspidoside | 3032517 |
| 111508-63-5 | - | Decoside | 441854 |
| 508-84-9 | - | Divaricoside | 120704 |
| 627-51-0 | - | Divinyl sulfide | 12321 |
| 76704-78-4 | - | Divostroside | 441857 |
| 61825-98-7 | 西贝母碱 | Imperialine | 442977 |
| 5989-02-6 | 黑麦草内酯,地芰普内酯 | Loliolide | 100332 |
| 58493-47-3 | - | N-Vanillyloctanamide | 5316427 |
| 76-28-8 | - | Sarmentogenin | 6437 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ACLY | ACL; ATPCL; CLATP | 17q21.2 | 24690568 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21440986 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 24690568 |
| CASP7 | CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3 | 10q25.3 | 24690568 |
| ERBB2 | CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1 | 17q12 | 24994678 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 21440986 |
| MTOR | FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS | 1p36.22 | 21440986 |
| PARP1 | ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1 | 1q42.12 | 24690568 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Bone neoplasms | group | 21440986 |
| Lung Neoplasms | group | 23340170 |
| Neoplasm Metastasis | phenotype | 24994678 |
| Osteosarcoma | disease | 21440986 |
| Prostatic Neoplasms | group | 24690568 |
