1. 药材主信息
| 中文名称: | 小连翘 |
| 英文名称: | Erect StJohn’swort |
| 拉丁名称: | Hypericum erectum |
| 使用部位: | whole herb |
| 功用: | To regulate menstruation and stanch bleeding, dissipate stasis and relieve pain, resolve toxin and disperse swelling. |
| 适用症: | Blood ejection, hemoptysis, spontaneous external bleeding, hematochezia, flooding and spotting, bleeding due to external injury, menstrual disorder, postpartum galactostasis, knocks and falls, pain in joints due to rheumatalgia, swelling toxin of sore and boil, poisonous snake bite. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 6468-55-9 | 去甲蟛蜞菊内酯 | Demethylwedelolactone | 5489605 |
| 11079-53-1 | 贯叶金丝桃素 | Hyperforin | 441298 |
| 548-04-9 | 金丝桃素 | Hypericin | 3663 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| LONP1 | CODASS; LON; LONP; LonHS; PIM1; PRSS15; hLON | 19p13.3 | 31683954 |
| MMP9 | CLG4B; GELB; MANDP2; MMP-9 | 20q13.12 | 20883786 |
| TRPC6 | FSGS2; TRP6 | 11q22.1 | 23814119 |
| TRPC6 | FSGS2; TRP6 | 11q22.1 | 27881772 |
| TRPC6 | FSGS2; TRP6 | 11q22.1 | 31683954 |
| VEGFA | MVCD1; VEGF; VPF | 6p21.1 | 20883786 |
| ZFYVE9 | MADHIP; NSP; PPP1R173; SARA; SMADIP | 1p32.3 | 31867163 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Neoplasms | group | 20883786 |
| Cerebellar Neoplasms | group | 20883786 |
| Glioblastoma | disease | 20883786 |
| Medulloblastoma | disease | 20883786 |
