1. 药材主信息
| 中文名称: | 小蓟 |
| 英文名称: | Field Thistle Herb |
| 拉丁名称: | Herba Cirsii;Herba Cirsii segeti |
| 使用部位: | whole herb or root |
| 功用: | To arrest bleeding by reducing heat in blood, and to remove blood stasis and induce the subsidence of swelling. |
| 适用症: | Coughing of blood, blood ejection, spontaneous external bleeding, hematuria, blood strangury, hematochezia, blood dysentery, flooding and spotting, bleeding due to external injury, swelling toxin of welling abscess and flat abscess. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 28351-05-5 | 三十烷醇 | 1-Triacontanol | 68972 |
| 541-91-3 | 麝香酮 | 3-Methylcyclopentadecanone | 10947 |
| 1021950-79-7 | 金莲花碱 | 8,9-Dihydroxy-1,5,6,10B-tetrahydropyrrolo[2,1-A]isoquinolin-3(2H)-one | 21574476 |
| 480-44-4 | 金合欢素;刺槐素 | Acacetin | 5280442 |
| 520-36-5 | 芹菜素 | Apigenin | 5280443 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 331-39-5 | 咖啡酸 | Caffeic Acid | 689043 |
| 120-80-9 | 儿茶酚 | Catechol | 289 |
| 327-97-9 | 绿原酸 | Chlorogenic Acid | 1794427 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKR1B1 | ADR; ALDR1; ALR2; AR | 7q33 | 21712449 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20840540 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| BAX | BCL2L4 | 19q13.33 | 30326282 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Atrial Fibrillation | disease | 21906601 |
| Blood Pressure | phenotype | 28143892 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Epstein-Barr Virus Infections | group | 28056971 |
| Esophageal Neoplasms | group | 26603620 |
| Fibrosis | phenotype | 28143892 |
