1. 药材主信息
| 中文名称: | 夏枯草 |
| 英文名称: | fruit -spike of Common Selfheal |
| 拉丁名称: | Spica Prunellae |
| 使用部位: | spike |
| 功用: | To quench fire of the liver and counteract inflammation of the eye, and to reduce modulation and induce subsidence of swelling. |
| 适用症: | Red eyes with gall, eyeball night pain, headache and dizziness, scrofula, goiter and tuberculosis, mammary welling abscess, thyroid enlargement, scrofula, hyperplasia of mammary glands, hypertension. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 99-83-2 | 水芹烯 | - | 7460 |
| 51685-40-6 | - | (+)-Linalyl acetate | 6999980 |
| 7787-20-4 | (-)-小茴香酮 | (-)-Fenchone | 82229 |
| 2217-02-9 | - | (1R)-endo-(+)-Fenchyl alcohol | 6997371 |
| 521-03-9 | - | 24-Ethyl-5alpha-cholest-7-en-3beta-ol | 131751392 |
| 16727-30-3 | 氯化锦葵色素苷 | 3,5-Bis(beta-D-glucopyranosyloxy)-7-hydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-1-benzopyrylium chloride | 5319251 |
| 512-13-0 | - | alpha-Fenchol | 439711 |
| 4221-98-1 | - | alpha-PHELLANDRENE, (-)- | 442482 |
| 481-18-5 | α-菠菜甾醇 | alpha-Spinasterin | 5281331 |
| 481-18-5 | α-菠菜甾醇 | alpha-Spinasterin | 5281331 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 23360684 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27393705 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Cognition Disorders | group | 21708244 |
| Colitis | disease | 25281414 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Diabetes | disease | 28049156 |
| Diabetes | disease | 28707095 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Hyperglycemia | disease | 23471488 |
