科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 五味子
英文名称: Chinese Magnoliavine Equivalent plant: Schisandra
拉丁名称: Schisandra chinensis
使用部位: fruit
功用: To promote contraction and secure astriction, boost qi and engender liquid, quiet heart and spirit.
适用症: Enduring cough and vacuity asthma, dream emission, frequent urination and enuresis, incessant chronic diarrhea, spontaneous sweating and night sweating, fluid damage and thirst, palpitation and insomnia.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
106-22-9 β-香茅醇 - 8842
495-61-4 (-)-β-bisabolene - 10104370
7785-70-8 (1R)-(+)-alpha-蒎烯 (+)-alpha-Pinene 82227
7785-53-7 - (+)-alpha-Terpineol 442501
19912-83-5 - (-)-alpha-Chamigrene 442351
20307-83-9 Β- 倍半水芹烯 (-)-beta-Sesquiphellandrene 12315492
1135-66-6 Isolongifolene (-)-Isolongifolene 11127402
115-71-9 - (Z)-5-[(1S,3R)-2,3-dimethyl-3-tricyclo[2.2.1.02,6]heptanyl]-2-methylpent-2-en-1-ol 24832102
1076-56-8 5-甲基-2-异丙基苯甲醚 2-Isopropyl-5-methylanisole 14104
136-83-4 - 2-Nonylphenol 67296

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
AIF1 AIF-1; IBA1; IRT-1; IRT1 6p21.33 28544365
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 28428076
ALDH3A1 ALDH3; ALDHIII 17p11.2 29794221
ALOX15 12-LOX; 15-LOX; 15-LOX-1; LOG15 17p13.2 30130298
CDK5 LIS7; PSSALRE 7q36.1 31163256
COL11A2 DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3 6p21.32 22251058
FGB HEL-S-78p 4q31.3 26249791
GLP1R GLP-1; GLP-1-R; GLP-1R 6p21.2 28270518
GSK3B - 3q13.33 22142471
IGF1 IGF; IGF-I; IGFI; MGF 12q23.2 28544365

4. 相关疾病