1. 药材主信息
| 中文名称: | 五灵脂 |
| 英文名称: | Trogopterus Dung |
| 拉丁名称: | Trogopterus xanthipes, Pteromys volans |
| 使用部位: | dried feces |
| 功用: | To quicken blood and relieve pain, transform stasis and stanch bleeding, disperse accumulation and resolve toxin. |
| 适用症: | Amenorrhea, postpartum blood stasis abdominal pain, flooding, profuse menstruation, incessant red and white vaginal discharge, snake bite, scorpion sting, centipede bite. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 80-57-9 | - | (1R,5S)-4,6,6-trimethylbicyclo[3.1.1]hept-3-en-2-one | 6973628 |
| 99282-79-8 | 2-(CARBOXYMETHYL-AMINO)-4-CHLORO-BENZOIC ACID | 2-((Carboxymethyl)amino)-4-chlorobenzoic acid | 11107141 |
| 3067-10-5 | - | 5-Methoxy-7-hydroxycoumarin | 5487854 |
| 97-59-6 | 尿囊素 | Allantoin | 204 |
| 7559-04-8 | 托可醌 | alpha-Tocopherolquinone | 2734086 |
| 120-80-9 | 儿茶酚 | Catechol | 289 |
| 10504-35-5 | - | D-ascorbic acid | 54690394 |
| 492-62-6 | - | D-Glucose | 5793 |
| 68-94-0 | 次黄嘌呤 | Hypoxanthine | 135398638 |
| 78-59-1 | 异佛尔酮 | Isophorone | 6544 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| BBC3 | JFY-1; JFY1; PUMA | 19q13.32 | 24389342 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 22832932 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 27472952 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 22832932 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 27472952 |
| BIRC5 | API4; EPR-1 | 17q25.3 | 22832932 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Cognition Disorders | group | 21708244 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Inflammation | phenotype | 21708244 |
| leukemia | disease | 23584398 |
| leukemia | disease | 21950524 |
| Liver Cirrhosis, Experimental | disease | 21168456 |
| Liver neoplasms | group | 27036874 |
| Lung Neoplasms | group | 26362062 |
